Extensive as the literature of purpura is, the bulk of its discussion, in later years at least, is given over to pathology and to classification, while the treatment, especially of the severer forms, ambling through many diverse paths, is still far from satisfying; and must remain unsatisfactory no doubt, until its etiology has passed from the domain of interesting speculation to that of empirical fact. In view of the increasing interest in serum-therapy, and because its use has been advocated mainly in hemophilia, it has seemed justifiable to report the following case.
A brief modern history of the treatment of purpura may serve, if only by contrast, to heighten the striking effects recently obtained in some cases through the use of serum. David King, Jr., in his Fiske Prize Essay (1836) gave the following summary of the best methods then in use:
Blood-letting was the great remedy
CLASS FM. SERUM-THERAPY IN PURPURA HEMORRHAGICA: WITH REPORT OF A CASE. Arch Intern Med (Chic). 1910;VI(2):170–174. doi:10.1001/archinte.1910.00050300051004
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