The following observations were thought to be of value because they add to the number of reported cases of a somewhat rare disease and because I believe that they throw some light on an obscure and much-discussed subject. The report of a case of Hodgkin's disease running an acute course, the diagnosis of two other cases by the examination of lymph-nodes removed surgically, the report of a case of tuberculous lymphadenitis whose histologic appearance closely simulated that of Hodgkin's disease, and a case of Hodgkin's disease that appears to have undergone sarcomatous transformation, form a series from which, with other observations from the literature, certain well-supported conclusions may be drawn.
I shall not go into a wearying presentation of the literature, which has been reviewed most completely in the papers by Reed,1 Longcope,2 and Yamasaki,3 and in some of the more extensive articles such as those
KARSNER HT. A STUDY OF CASES OF HODGKIN'S DISEASE AND CERTAIN ALLIED CONDITIONS. Arch Intern Med (Chic). 1910;VI(2):175–195. doi:10.1001/archinte.1910.00050300056005
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