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Article
November 1910

A CASE OF FATAL SODIUM CHLORID POISONING: WITH A BRIEF STUDY OF THE EFFECTS OF THE EXCESSIVE ADMINISTRATION OF SALT ON THE TISSUES

Arch Intern Med (Chic). 1910;VI(5):577-585. doi:10.1001/archinte.1910.00050330112007
Abstract

All are more or less familiar with the effects which follow the excessive administration of sodium chlorid, especially with those of such minor grades as arise, for example, after the ingestion of meats or other foods highly salted or after drinking of water rich in sodium chlorid. Indeed, it is highly probable that the early death said to occur when, other water lacking, sea-water is taken as a beverage, is due for the most part to the direct action of the salt and its effect on the tissues of the body. When through choice or necessity, salt foods are taken in excess and when, at the same time, one is unable to secure the requisite amount of water which Nature demands in this condition, symptoms arise illustrative of the effects of excessive amounts of sodium chlorid. This is a fact well appreciated by frontiersmen, explorers, soldiers, by the primitive

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