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Article
March 1911

ACUTE YELLOW ATROPHY OF THE LIVERREPORT OF TWO CASES

Arch Intern Med (Chic). 1911;VII(3):376-382. doi:10.1001/archinte.1911.00060030089006

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Abstract

CLINICAL AND PATHOLOGICAL STUDY, BY DR. NOVAK  Not only the rarity of this disease, but also the probable relation which it bears to certain other interesting conditions—the obstetrical toxemias, delayed chloroform poisoning, etc.—has induced us to report these two cases. According to Dr. J. Wickham Legg, who made a rather elaborate study of the history of this disease, the first description of the condition was given by Ballonius, who died in 1616. It was not, however, until 1843 that the name "acute yellow atrophy" was bestowed on the disease by Rokitansky. That the condition is a rare one can be appreciated from the fact that the total number of reported cases in all probability does not exceed 450. Out of 25,000 cases admitted to the London Fever Hospital during a period of nine years Murchison encountered only one case of this disease, while only three cases have occurred

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