Widal, Achard, and Strauss some years ago called attention to the bearing of sodium chlorid retention on the still unsettled question of nephritic edema, and since then regulation of the chorid intake has been found of value, not only in nephritis, but also in the treatment of fluid accumulations of other origins. The measure has been applied with more or less success in cases of cardiac disease, inflammatory exudates, such, for example, as tuberculous peritonitis, and diabetes insipidus, and in conditions in which it is desirable to restrict the amount of fluid ingested. It is chiefly in nephritis, however, that resort to a salt-poor diet has been found useful, and it is becoming evident that while the therapeutic results are not invariably so brilliant as Widal predicted, investigation of the chlorid tolerance can furnish valuable diagnostic and prognostic indications. According to Widal, two clinical types of nephritis may be recognized,
VOGEL KM. CHLORID AND WATER TOLERANCE IN NEPHRITIS. Arch Intern Med (Chic). 1911;VII(5):602–609. doi:10.1001/archinte.1911.00060050024003
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