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July 1911


Author Affiliations


Arch Intern Med (Chic). 1911;VIII(1):58-59. doi:10.1001/archinte.1911.00060070063004

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At the time that Dr. Hawk was conducting his experiments on the effects of ether anesthesia on the metabolism of dogs, I was pathologist to St. Mary's Hospital, of Philadelphia. I was interested in the fact that many of the dogs subjected to prolonged anesthesia had glucose in their urines for varying periods after the administration of the ether. I undertook at that time to see whether ether as administered in the course of the regular surgical service of a hospital was in any case followed by the excretion of glucose. The plan was to record the time of the beginning of the administration of the anesthetic, the time that the administration was discontinued, the quantity of ether used, and whether there were any complications of anesthesia during the administration of the ether. Then the urine was to be collected as it was passed for at least two days

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