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August 1911


Author Affiliations


From the Laboratories of Physiological Chemistry of the University of Illinois and of the Department of Medicine of the University of Pennsylvania.

Arch Intern Med (Chic). 1911;VIII(2):177-182. doi:10.1001/archinte.1911.00060080057007

In a previous paper1 I reported the data from a series of experiments on the diuresis following ether anesthesia. In those experiments, which were made on dogs, it was shown that ether narcosis induced for periods varying in length from thirty minutes to four and one-half hours was followed in every instance by an initial diuresis, the extent of the diuresis being proportional, in some instances, to the length of the anesthesia period. This point was well illustrated by the initial diureses of 5.7 per cent., 6.8 per cent., 12.9 per cent. and 24.8 per cent, which followed ether anesthesia periods of one-half, one, two and four and one-half hours respectively. It was further shown in these experiments that the diuretic effect of the ether was persistent in every case except one. The ultimate average daily percentage increase in the urine volume ranged from 3.1 per cent. to 20.7