1. INTRODUCTION
The sixty-nine cases used as the basis of this report include all cases clinically diagnosed as exophthalmic goiter at Lakeside Hospital from Sept. 7, 1907, to Sept. 7, 1910, from which sufficient thyroid gland tissue was obtained for anatomical studies and for iodin determinations.The principal data appertaining to each case have been tabulated as briefly as possible (Table 3). It will be noticed that special stress is laid on the objective phenomena obtained during the patient's stay in the hospital. This was done (1) because we have as yet no accurate standard of estimating the importance of subjective sensations in this disease, although they are doubtless of great importance in all nervous and mental diseases, and (2) because our major interest at present is concerned with the physiological relation of the thyroid gland to the symptom-complex.
2. PATHOLOGICAL ANATOMY
In describing the pathological anatomy of exophthalmic goiter