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Article
September 1911

THE IMMEDIATE EFFECT ON THE COMPLEMENT FIXATION TEST FOR LUES OF TREATMENT WITH SALVARSAN (ARSENOBENZOL)AN ANALYSIS OF 225 CASES

Arch Intern Med (Chic). 1911;VIII(3):395-416. doi:10.1001/archinte.1911.00060090132006
Abstract

In reviewing the literature on the results of the treatment of lues with salvarsan, one is impressed with the unsatisfactory nature of the data regarding the effect of treatment with this drug on the complement fixation test. It is now generally acknowledged that this test is the only exact index we possess of the efficacy of any method of treatment of lues; indeed, Ehrlich1 does not hesitate to say that "the observation of the Wassermann reaction represents the most valuable method we have of seeing clearly whether the syphilis is genuinely cured," and this opinion is supported by every authority having to do with the treatment of the disease.

In view of the importance of the complement fixation test as a control of the efficacy of treatment with salvarsan, I have thought that an analysis of 225 cases, showing the immediate effect of such treatment on the

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