Working with richly infected material from kittens infected rectally with E. tetragena, very interesting forms were detected in a senile race. These are so much like Hartmann's figures of Schaudinn's preparations illustrating the spore cyst development of E. histolytica as to be practically identical with them. They also correspond very closely with Schaudinn's1 and Craig's2 descriptions of the alleged perpetuating forms of E. histolytica.Hartmann3 has called attention to the wide-spread distribution of E. tetragena, and has expressed his opinion that most of Schaudinn's histolytica material is really E. tetragena.In Panama, while the perpetuating forms of E. tetragena (cysts) have been detected in a number of cases, nothing save some budding forms in fresh material from one fatal case, and the remarkable forms in rectally infected kittens have ever been seen by me which resemble the descriptions of Schaudinn and Craig for the spore
DARLING ST. BUDDING AND OTHER FORMS IN TROPHOZOITES OF ENTAMOEBA TETRAGENA: SIMULATING THE ``SPORE CYST'' FORMS ATTRIBUTED TO ``ENTAMOEBA HISTOLYTICA''. Arch Intern Med (Chic). 1913;XI(5):495–506. doi:10.1001/archinte.1913.00060290029003
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