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The first edition of Bredl's splendid compilation of the literature, and his own experience on the glands of internal secretion, appeared in 1910. The early appearance of the new edition demonstrates how much need there was for such a work, and how well supplied the need was. But this is more than a new edition — it is an entirely new work; for while the entire book in its first edition was but about 400 pages, the first volume alone of the second edition contains 130 more. The author seems to have felt that in his first work the limited use of space preventea him from going into the detail which the unsettled state of many of his problems really demanded for their presentation. The need for explanation by means of illustrations has been filled by twenty colored plates and a great number of blackand-w hites. In this