Typhoid fever with its well-known clinical and pathological picture may present itself in various atypical forms. Louis, in 1829, was apparently the first observer to note the disease without the usual intestinal lesions. Dittrich (1846), Lebert (1858) and Guyot (1870) contributed additional cases to the literature. Since the typhoid bacillus was not discovered and its etiological significance established by Eberth and Gaffky until 1880 and 1884, these early cases are open to question. Morre,1 in 1880, reported a case of splenotyphoid with suppurative changes in the spleen and no demonstrable intestinal lesions. One year later Mader2 reported a case of bronchotyphoid, while Church,3 in 1882, reported three cases of extra-intestina type. Among many others specifically described below, Vaillard4 (1890), Phillips5 and Beatty6 (1897), Lartigau,7 Richardson,8 Howard9 and Bryant10 (1899), Turney11 (1900), Opie and Bassett12 (1901)
CUMMINS WT, BROWN PK. ATYPICAL TYPHOID INFECTION. Arch Intern Med (Chic). 1913;XII(4):357–371. doi:10.1001/archinte.1913.00070040002001
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: