A number of authors, Marey,1 Fredericq,2 Lazarus,3 Crile4 and Henderson5 among them, have presented either a review or their conceptions of the changes produced in the circulation during hemorrhage. Each of these writers has reflected the knowledge available at the time and much that has already been said can merely be reechoed. For a number of years, however, I have been collecting experimental evidence which, in some instances, extends or interrelates the observations already established and, in others, appears to necessitate a revision of current views. Hence, although many problems still await investigation, the attempt is made to present such a picture of the pathological changes in the circulation during hemorrhage as appears justifiable in the light of present-day knowledge. In doing this the hope is entertained that such an exposition may prove of value in interpreting the signs or
WIGGERS CJ. THE PATHOLOGIC PHYSIOLOGY OF THE CIRCULATION DURING HEMORRHAGE. Arch Intern Med (Chic). 1914;XIV(1):33–47. doi:10.1001/archinte.1914.00070130040003
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