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January 1917


Author Affiliations

Assistant Physician to the Neurological Institute, New York City; Consulting Neurologist, New Rochelle and Volunteer Hospitals ; Visiting Neurologist, Randall's Island Institutions NEW YORK

Arch Intern Med (Chic). 1917;XIX(1):79-104. doi:10.1001/archinte.1917.00080200084004

In the present paper, the author desires to report a somewhat atypical form of progressive muscular dystrophy, rather resembling Erb's infantile type, of extremely benign and slow progress. In the cases examined it has occurred as a hereditary affection now in the fourth generation. The number of individuals disabled thus far has been fourteen. Of the seven living members with the disease, all but two have been examined by Roentgen ray, and of these five, four show distinct changes in the pineal gland, producing shadows in the roentgenogram. The evidence presented by the cases reported in the present paper, together with that of previous communications in this field, creates a strong probability of the existence of a close relationship between progressive muscular dystrophy and disease of the pineal gland.

In order to understand the evolution that has now placed this disease among the endocrinopathies, a rapid