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Article
February 1917

TYPHOIDIN QUOTIENTS: AN ANALYSIS OF THE FACTORS OF UNCERTAINTY IN THE CUTANEOUS TYPHOIDIN TEST

Author Affiliations

SAN FRANCISCO

From the Department of Medicine of the University of California Medical School.

Arch Intern Med (Chic). 1917;XIX(2):263-275. doi:10.1001/archinte.1917.00080210104005
Abstract

In connection with a recent study1 of the cutaneous typhoidin test, which was introduced by Gay and Force2 as an index of typhoid immunity, an objective method of reading such cutaneous diagnostic reactions was described. Instead of reporting the test as positive, negative or doubtful, from the general appearance of the inoculated spots, the diameters of the areolae are measured with a suitable millimeter gage, preferably one which can be set to the diameter to be measured without exhibiting the reading until afterward. The result of a test is recorded as the quotient of the diameter of the test areola divided by that of the control. The advantages of this procedure are, first, that after adjusting the gage to the diameters of the areolae, the bias of the observer can be entirely eliminated in expressing the results of the test, and, second, that the quotients so obtained

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