In September, 1913, we called attention to the apparent relation between the origin of new cases of pellagra and the employment of insanitary methods of sewage disposal. This relationship has been discussed in several subsequent publications of this commission, and we have offered the hypothesis that the methods of disposal of human wastes might prove to be a determining factor in the spread of pellagra in certain communities. A practical experiment was announced and described in our second progress report.2 Since that time our epidemiologic observations on this particular point have been supported by other independent observers in Charleston, S. C.,3 and in Nashville, Tenn.4
In the present communication we wish to present the results of the experiment begun in the community of Spartan Mills, Spartanburg, South Carolina, in 1913. This particular
SILER JF, GARRISON PE, Macneal WJ. AN EXPERIMENTAL TEST OF THE RELATION OF SEWAGE DISPOSAL TO THE SPREAD OF PELLAGRA. Arch Intern Med (Chic). 1917;XIX(5_I):683–694. doi:10.1001/archinte.1917.00080240002001
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