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February 1915


Author Affiliations


From the Department of Pathology of the College of Physicians and Surgeons, Columbia University.

Arch Intern Med (Chic). 1915;XV(2):286-302. doi:10.1001/archinte.1915.00070200108008

Though iodin in the form of inorganic iodids or as organic compounds has been used for years, and is one of the most important drugs in the Pharmacopeia, little is known concerning its action in the body. This lack of knowledge applies particularly to its effect in causing the absorption of necrotic material such as is found in gummas.

The results obtained with the iodids have been variously ascribed to their influence in the general metabolism of the body ; to their supposed action in causing a fall in blood-pressure ; to a change in the viscosity of the blood ; to a lymphocytosis ; to an increase in the activity of the lymphatics, and to the oxidizing properties of the nascent iodin.

Binz1 and Hinz2 believed its action to be due to the oxidizing properties of the nascent iodin, which, according to Hinz, renders the blood-vessels more permeable

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