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July 1915


Author Affiliations


From the Department of Pharmacology of the Cornell University Medical School, New York.

Arch Intern Med (Chic). 1915;XVI(1):1-32. doi:10.1001/archinte.1915.00080010006001

In the course of this investigation I have been struck by the small amount of accurate knowledge that we possess as to practical therapeutics. My experience has been almost exclusively in the laboratory and perhaps I have expected too high a standard in the clinic, but in this field of cardiac tonics alone I see an endless vista of questions to be solved in the clinic if only accurate observations are available. . . . But we have enough of inaccurate therapeutics already; what is needed is not statistical compilation, but an accurate study of each individual case and a careful and, if you will, an experimental investigation of each feature presented.1

There are probably no more valuable therapeutic agents in our materia medica than digitalis and its several allies and, although digitalis has been in wide clinical use since Withering first brought it

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