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Article
September 1915

STUDIES IN DIPHTHEROIDS: III. BACTERIA ISOLATED FROM ENLARGED GLANDS, ESPECIALLY IN HODGKIN'S DISEASE

Author Affiliations

PHILADELPHIA

From the William Pepper Clinical Laboratory, University of Pennsylvania.

Arch Intern Med (Chic). 1915;XVI(3):465-480. doi:10.1001/archinte.1915.00080030126010
Abstract

The object of this paper is to put on record observations on bacteriologic studies in adenopathies, especially Hodgkin's disease, in the light of the findings of Fraenkel, Much, de Negri, Mieremet, Rosenow, Bunting and others.

The descriptions given in literature of bacteria isolated from malignant lymphatic granulomas seem to indicate a considerable difference in character among the isolated strains. Early in my work on Hodgkin's disease, it became evident that while diphtheroids might be isolated from many cases of this disease, and indeed from other adenopathies, they varied in morphology and biology. Cultures were sent me by Dr. E. C. Rosenow of Chicago (marked R) and by Dr. J. A. Kolmer (marked K), and comparison of these two sets with those obtained at the Pepper Laboratory showed that the impression stated above was correct. It seemed well to tabulate all the diphtheroids at my command to see

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