Among the sources of error in human blood pressure measurements an important factor, which has received comparatively little attention, is variation in pressure between individual pulse waves or between groups of them. It is well known that undulations in systolic and diastolic pressure occur commonly in normal persons with each respiration or at somewhat longer intervals ; and among the cases of cardiac arrhythmia, there may be the widest pressure differences even between consecutive pulse waves. The custom of clinicians to accept the average or the highest of several determinations, or simply the first reading made, while tolerably meeting the needs of practice among cases with regular heart action, amounts to the roughest kind of guess-work in cases of marked arrhythmia. Mackenzie1 gave up the attempt to measure blood in cases of auricular fibrillation. It will be shown, however, that notwithstanding the great differences between individual waves
KILGORE ES. THE FRACTIONAL METHOD OF BLOOD PRESSURE DETERMINATION—A CONTRIBUTION TO THE STUDY OF BLOOD PRESSURE IN CARDIAC ARRHYTHMIAS. Arch Intern Med (Chic). 1915;XVI(6):939–954. doi:10.1001/archinte.1915.00080060051004
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