In a paper1 published in 1914 I endeavored, on the basis of a number of clinical and experimental observations, to make a contribution to our knowledge of the pathogenesis of the eye symptoms in exophthalmic goiter. I dwelt in that connection particularly on Landström's explanation of their origin, and, making reference to our present anatomic and clinical information, expressed my doubts as to the possibility of maintaining Landström's theory. The chief points on which I based my remarks were the following:
1. The "Landström muscle," or rather the musculus capsulopalpebralis (Hesser2), is so weak and so asymmetrically placed as to be hardly capable of producing alone the pronounced eye symptoms which are not infrequently observed in exophthalmic goiter. Above all, it is difficult to understand how a contraction of that muscle should produce a pronounced shifting forward of its posterior origin (of the region about the
TROELL A. SOME ATTEMPTS TO PRODUCE EXOPHTHALMOS EXPERIMENTALLY. Arch Intern Med (Chic). 1916;XVII(3):382–395. doi:10.1001/archinte.1916.00080090041004
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