The subject of purpura in this paper is treated from the standpoint of the relationship it bears to tuberculosis.
Several writers within the last two centuries have made observations on this phenomenon, endeavoring to find its cause and effect, and to discover the relation purpura has to other diseases with which it is associated.
Mackenzie1 says :
The great variety of supposed causes or associated conditions is sufficiently striking. Still more so is the fact that in one-third of 200 cases no explanation was offered for the purpura, though in several of the cases a necropsy was made. It will thus be seen how extremely complex is the pathology of purpura.All we can do in the present state of our knowledge is to accumulate further information and to exhaust every means—histological, bacteriological and chemical—in the investigation of cases.Osler2 also maintains "that purpura is obscure, and is
BAUCH S. THREE CASES OF PURPURA HEMORRHAGICA IN CHRONIC TUBERCULOSIS: WITH A BRIEF REVIEW. Arch Intern Med (Chic). 1916;XVII(3):444–452. doi:10.1001/archinte.1916.00080090103009
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