Since the writing of Paper 41 of this series an unusual amount of work has been published on the subject of the normal metabolism. It is now possible to calculate the normal baseline much more exactly than a year ago and it is therefore necessary to reconsider the whole question at this early date. The figures representing the average normal metabolism have been changed frequently since the study of the respiratory exchanges began and it may be said that the chief advance has depended on the fact that it has been possible to make the variation in the normal smaller and smaller each year. With the oldest type of large respiration chamber the range of heat production fluctuated enormously with the uncontrolled influences of muscular activity and the specific dynamic action of food. With the improved technic of Johansson and with the small apparatus of the
GEPHART FC, Du BOIS EF. CLINICAL CALORIMETRYTHIRTEENTH PAPER THE BASAL METABOLISM OF NORMAL ADULTS WITH SPECIAL REFERENCE TO SURFACE AREA. Arch Intern Med (Chic). 1916;XVII(6_2):902–914. doi:10.1001/archinte.1916.00080130054005
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