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September 1917


Arch Intern Med (Chic). 1917;XX(3):392-398. doi:10.1001/archinte.1917.00090030077004

The Schick test has found considerable favor as a reliable clinical test in showing the presence of immunity or susceptibility to diphtheria, and is being used more and more by a rapidly increasing number of physicians. The test is now employed as a routine procedure in a great many institutions, hospitals, and in the private practice of numerous physicians. Not only is the test used to indicate the immunity of the children, but it is also of great value in active immunization with diphtheria toxin-antitoxin. For this purpose the Schick test is used not only to select the susceptible individuals, but also to indicate the efficiency and the duration of the active immunity. The very reliability of the Schick test when carefully carried out, indicates that, in making the test, one should take definite precautions to use a toxin of standard strength and carefully observe the exact directions for technical