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November 1917


Author Affiliations


From the Medical Clinic of Joseph L. Miller at the Cook County Hospital, and the Laboratory of Physiologic Chemistry, College of Medicine University of Illinois.

Arch Intern Med (Chic). 1917;XX(5):716-724. doi:10.1001/archinte.1917.00090050077004

The degree of interest with which certain phases of therapeusis along nonspecific lines has been received would seem to indicate that clinical observation of such character must have been quite frequently, although the possible significance had escaped comment. Various German clinicians have, in recent times, emphasized the striking therapeutic effects achieved with this so-called "protein" therapy, a not inapt designation, conveying, as it does, not only the concept of the basic reacting agent, but implying, too, wide range of effectiveness as a therapeutic measure. The best results have undoubtedly been obtained in the arthritic processes, an extended series of observations on such cases having been published by Miller and Lusk,1 and Culver.2 They seem particularly favorable for treatment, because the contraindications are few and the objective and subjective evidence of improvement under treatment are directly observable.

In a paper published last year Jobling3 discussed some of the factors that were