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Article
January 1918

ANATOMIC OBSERVATIONS CONCERNING THE MECHANISM OF BILE RESORPTION IN JAUNDICE

Arch Intern Med (Chic). 1918;XXI(1):73-83. doi:10.1001/archinte.1918.00090070082007
Abstract

The manner in which bile is resorbed from the liver into the blood, general circulation and tissues presents much that is still unclear and uncertain.

The subject is complicated by our imperfect knowledge of the finer structure of the liver. For, while the direct relation of the liver cells to blood and bile capillaries is not quite definitely settled, there exists no agreement whatever as to the presence or absence of lymph channels in the acini. It is held by some that perivascular lymph sheaths lie between liver cells and capillaries,1 while others positively deny this.2

The question, then, as to whether bile resorption in the liver occurs as the result of primary lymph or direct blood resorption, is complicated by anatomic uncertainty.

The physiologic experiment is unable to solve this problem, for not only are the observations and conclusions of experimenters quite contradictory,3 but lymph and blood have naturally

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