THE SUPERIORITY OF INOCULATIONS WITH MIXED TRIPLE VACCINE (B. TYPHOSUS, B. PARATYPHOSUS A, AND B. PARATYPHOSUS B): OVER SUCCESSIVE INOCULATIONS WITH THE SINGLE VACCINES, AS SHOWN BY AGGLUTININ CURVES IN MEN AND RABBITS

At present the subject of immunity against the enteric fevers, that is, typhoid, paratyphoid A and paratyphoid B, is of the utmost importance. Records of the Franco-German War, of the Boer War,¹ of the Russo-Japanese War² and of the Spanish-American War³ clearly show that the number of deaths from enteric fevers in those wars was approximately half of that due to wounds. Therefore, the problem of producing immunity against the enteric fevers has occupied the minds of many investigators. The success of the work done by Wright, Kabeshima² and others in regard to immunity against typhoid fever has been admirably demonstrated by its practical application in the armies of the United States, of Japan and of all the countries now at war (1917). It may safely be stated that since prophylactic vaccination against typhoid fever has been made more or less universal among armies, the losses from that disease have