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June 1918


Author Affiliations

University Hospital MINNEAPOLIS

From the Chemical Laboratory, Department of Medicine, University of Minnesota.

Arch Intern Med (Chic). 1918;XXI(6):705-715. doi:10.1001/archinte.1918.00090110002001

So-called renal diabetes has been reported at various times in the literature. The term is now recognized as a misnomer and the condition should be called renal glycosuria. True cases of renal glycosuria are rare and many so diagnosed are open to question, being mild or atypical diabetes mellitus.

The lesion is apparently renal and due to a constant excretion by the kidney of a small amount of sugar while the blood sugar is normal. The tissues can still utilize carbohydrates, and as a result on any diet the percentage of sugar excreted does not vary to any great extent. The glycosuria is usually found by accident or routine examination, the patient reporting for life insurance or irrelevant illness. Most of the patients do not present any of the clinical symptoms of diabetes mellitus and are apparently in good health. Pathologically, the glycosuria seems to be due to a lowered