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Editor's Correspondence
December 8/22, 2003

Vascular Protection of ACE Inhibitors

Arch Intern Med. 2003;163(22):2791-2792. doi:10.1001/archinte.163.22.2791-a

In their enthusiastic review on the renin-angiotensin system and atherothrombotic disease,1 Jacoby and Rader state that

. . . the PROGRESS (Perindopril Protection Against Recurrent Stroke Study) found that angiotensin-converting enzyme (ACE) inhibition in 6105 patients with a history of cardiovascular accidents or transient ischemic attacks reduced the secondary outcome of cardiac death or acute MI. . . .

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