In their enthusiastic review on the renin-angiotensin system and atherothrombotic disease,1 Jacoby and Rader state that
. . . the PROGRESS (Perindopril Protection Against Recurrent Stroke Study) found that angiotensin-converting enzyme (ACE) inhibition in 6105 patients with a history of cardiovascular accidents or transient ischemic attacks reduced the secondary outcome of cardiac death or acute MI. . . .
Messerli FH. Vascular Protection of ACE Inhibitors. Arch Intern Med. 2003;163(22):2791–2792. doi:10.1001/archinte.163.22.2791-a
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