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Editor's Correspondence
December 8/22, 2003

Cost-effective, Risk-Free, Evidence-Based Medicine—Reply

Author Affiliations

Copyright 2003 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2003

Arch Intern Med. 2003;163(22):2795-2796. doi:10.1001/archinte.163.22.2795-a

In reply

There are a number of points raised by Dr Matz. First, he questions whether an abnormal ABI adds value to readily available proven diagnostic and therapeutic protocols. He comments specifically about a good history review. It is notoriously difficult to obtain a diagnosis of PAD from a history review because many patients are asymptomatic or do not present with classic symptoms.1-3 Only around one third of people with PAD (as defined by ABI <0.9) will report classic claudication symptoms. A further third will not mention their symptoms to their physician or will have confused them with a musculoskeletal diagnosis. The remaining third will have no relevant symptoms whatsoever. All of these people are at increased risk of future cardiovascular events, whether they are symptomatic or not. The ABI test identifies many at-risk patients who would not be detected by taking a conventional history, and would not, therefore, be treated aggressively for vascular risk factors.