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Editor's Correspondence
December 11/25, 2006

Positive Outcomes Through the Appropriate Use of Off-Label Prescribing

Arch Intern Med. 2006;166(22):2554-2555. doi:10.1001/archinte.166.22.2554-b

I am writing on behalf of the National Mental Health Association (NMHA) in response to the article titled “Off-label Prescribing Among Office-Based Physicians” by Radley et al.1

As an organization, NMHA is concerned with the inappropriate prescribing of medications; however, we are also concerned about the potential to conclude from the study by Radley et al,1 that all off-label prescribing is inappropriate. The study's conclusion that off-label use of medications lacks rigorous scientific scrutiny has strong implications and could lead to a false assumption about the usefulness of off-label prescribing.