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September 2019, Vol 179, No. 9, Pages 1157-1308

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
free access
JAMA Intern Med. 2019;179(9):1157-1159. doi:10.1001/jamainternmed.2018.5511
Viewpoint

Preclinical Alzheimer Disease—Early Diagnosis or Overdiagnosis?

Abstract Full Text
JAMA Intern Med. 2019;179(9):1161-1162. doi:10.1001/jamainternmed.2019.2629

This Viewpoint argues that the shift from treating patients with symptomatic Alzheimer disease to treating those with preclinical disease carries the risk of overdiagnosis.

The Ketogenic Diet for Obesity and Diabetes—Enthusiasm Outpaces Evidence

Abstract Full Text
JAMA Intern Med. 2019;179(9):1163-1164. doi:10.1001/jamainternmed.2019.2633

This Viewpoint assesses the risks and benefits associated with the ketogenic diet for treatment of obesity and type 2 diabetes.

Original Investigation

Regression to the Mean in the Medicare Hospital Readmissions Reduction Program

Abstract Full Text
JAMA Intern Med. 2019;179(9):1167-1173. doi:10.1001/jamainternmed.2019.1004

This analysis quantifies the contribution of regression to the mean to declining readmission rates at hospitals initially penalized under the Medicare Hospital Readmissions Reduction Program.

Less Is More

Association Between Inpatient Echocardiography Use and Outcomes in Adult Patients With Acute Myocardial Infarction

Abstract Full Text
JAMA Intern Med. 2019;179(9):1176-1185. doi:10.1001/jamainternmed.2019.1051

This cohort study uses a large multihospital database to evaluate the association between hospital rates of echocardiogram use and outcomes in adult patients with acute myocardial infarction.

Association of Opioid Overdose With Opioid Prescriptions to Family Members

Abstract Full Text
JAMA Intern Med. 2019;179(9):1186-1192. doi:10.1001/jamainternmed.2019.1064

This case-control study uses more than 25 million insurance claims to assess whether individuals who did not receive an opioid prescription had greater odds of overdose when a opioid prescription was dispensed to a family member.

Association Between Electronic Cigarette Use and Smoking Reduction in France

Abstract Full Text
JAMA Intern Med. 2019;179(9):1193-1200. doi:10.1001/jamainternmed.2019.1483

This cohort study examines the association of the regular use of electronic cigarettes with the number of cigarettes smoked per day, smoking cessation among current smokers, and smoking relapse among former smokers in France.

Health Care Policy and Law

Financial Implications of 12-Month Dispensing of Oral Contraceptive Pills in the Veterans Affairs Health Care System

Abstract Full Text
JAMA Intern Med. 2019;179(9):1201-1208. doi:10.1001/jamainternmed.2019.1678

This economic decision model estimates the financial and reproductive health implications for implementation of a 12-month option for dispensing oral contraceptive pills in the Veterans Affairs health care system.

Less Is More

Prevalence and Cost of Care Cascades After Low-Value Preoperative Electrocardiogram for Cataract Surgery in Fee-for-Service Medicare Beneficiaries

Abstract Full Text
has active quiz
JAMA Intern Med. 2019;179(9):1211-1219. doi:10.1001/jamainternmed.2019.1739

This cohort study reviews data from fee-for-service Medicare beneficiaries without known heart disease who underwent cataract surgery to compare care cascades (tests, treatments, visits, hospitalizations, a and new diagnoses) between those who received preoperative electrocardiograms and those who did not.

Diagnosis and Management of Primary Hyperparathyroidism Across the Veterans Affairs Health Care System

Abstract Full Text
JAMA Intern Med. 2019;179(9):1220-1227. doi:10.1001/jamainternmed.2019.1747

This cohort study examines the appropriateness of diagnostic evaluation for primary hyperparathyroidism in patients with hypercalcemia and the use of parathyroidectomy for the treatment of primary hyperparathyroidism across the Veterans Affairs health care system.

Strategies to Identify Women at High Risk of Advanced Breast Cancer During Routine Screening for Discussion of Supplemental Imaging

Abstract Full Text
JAMA Intern Med. 2019;179(9):1230-1239. doi:10.1001/jamainternmed.2019.1758

This cohort study assesses strategies to identify women at high risk of advanced breast cancer to target patient-practitioner discussions about the need for supplemental imaging.

Nabiximols for the Treatment of Cannabis Dependence: A Randomized Clinical Trial

Abstract Full Text
JAMA Intern Med. 2019;179(9):1242-1253. doi:10.1001/jamainternmed.2019.1993

This randomized clinical trial examines the safety and efficacy of nabiximols, an oromucosal tetrahydrocannabinol-cannabidiol medication vs placebo, in the treatment of adults with cannabis dependence.

Adverse Events in Long-term Care Residents Transitioning From Hospital Back to Nursing Home

Abstract Full Text
JAMA Intern Med. 2019;179(9):1254-1261. doi:10.1001/jamainternmed.2019.2005

This cohort study evaluates records of 555 residents of 32 New England nursing homes who returned to their nursing homes after hospitalization to measure the frequency, severity, and preventability of adverse events in the 45 days after hospitalization.

Association of Weight Loss Interventions With Changes in Biomarkers of Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis

Abstract Full Text
open access has audio
JAMA Intern Med. 2019;179(9):1262-1271. doi:10.1001/jamainternmed.2019.2248

This systematic review and meta-analysis evaluates 22 randomized clinical trials including 2588 participants with nonalcoholic fatty liver disease (NAFLD) who underwent interventions to determine whether these interventions were associated with changes in NAFLD biomarkers.

Editorial

Ending AIDS in the United States—If Not Now, When?

Abstract Full Text
JAMA Intern Med. 2019;179(9):1165-1166. doi:10.1001/jamainternmed.2019.1577

This Editorial discusses the importance of quickly implementing the latest US Preventive Services Task Force recommendations for HIV screening and preexposure prophylaxis.

Invited Commentary

The Medical Hospital Readmission Reduction Program: Does It Do Any Good?

Abstract Full Text
JAMA Intern Med. 2019;179(9):1174-1175. doi:10.1001/jamainternmed.2019.1003

Expanding Access to Short-Acting Hormonal Contraceptive Methods in the United States

Abstract Full Text
JAMA Intern Med. 2019;179(9):1209-1210. doi:10.1001/jamainternmed.2019.1676

Applying the Guidelines for Primary Hyperparathyroidism: The Path Not Taken

Abstract Full Text
JAMA Intern Med. 2019;179(9):1227-1229. doi:10.1001/jamainternmed.2019.1738

Advising Women About Supplemental Screening After Dense Breast Notification: Still No Easy Answers

Abstract Full Text
JAMA Intern Med. 2019;179(9):1240-1241. doi:10.1001/jamainternmed.2019.1737

Treatment of Fatty Liver Disease—Time to Implement Common Sense Measures

Abstract Full Text
has audio
JAMA Intern Med. 2019;179(9):1272-1273. doi:10.1001/jamainternmed.2019.2244

Digital Breast Tomosynthesis—Diffusion Into Practice Preceding Evidence

Abstract Full Text
JAMA Intern Med. 2019;179(9):1295-1296. doi:10.1001/jamainternmed.2019.1037

Longevity Among Major League Baseball Players—Play Ball!

Abstract Full Text
JAMA Intern Med. 2019;179(9):1301-1302. doi:10.1001/jamainternmed.2019.1195
Editor's Note

Interventional Cardiology Payments and Device Choices—The Ties That (May) Blind

Abstract Full Text
JAMA Intern Med. 2019;179(9):1284-1285. doi:10.1001/jamainternmed.2018.8737
Teachable Moment

Coagulation Testing in Patients Taking Direct Oral Anticoagulants: A Teachable Moment

Abstract Full Text
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JAMA Intern Med. 2019;179(9):1274-1275. doi:10.1001/jamainternmed.2019.1799

This Teachable Moment examines the case of a man taking a direct oral anticoagulant (DOAC) who received a high international normalized ratio (INR) test result during a visit to the emergency department and suggests that INR is an unreliable measure of therapeutic anticoagulation in patients taking DOACs.

Selecting the Appropriate Patients for Proton Pump Inhibitor Discontinuation: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2019;179(9):1276-1277. doi:10.1001/jamainternmed.2019.2382

This Teachable Moment examines the case of a man in his 70s who presented to the emergency department 2 weeks after discontinuation of proton pump inhibitors (PPIs) to caution against abrupt PPI discontinuation in patients with multiple risk factors for peptic ulcer disease.

Research Letter

Health Care Policy and Law

Distribution of Industry Payments Among Medical Directors of Catheterization and Electrophysiology Laboratories From the Top 100 US Hospitals

Abstract Full Text
JAMA Intern Med. 2019;179(9):1282-1284. doi:10.1001/jamainternmed.2018.8775

This analysis of 2017 data from the Open Payments Program (OPP) database examines nonresearch industry payments to directors of caronary catheterization and electrophysiology laboratories to characterize payments across 13 OPP-defined categories.

Trends in Proportion of Women as Authors of Medical Journal Articles, 2008-2018

Abstract Full Text
JAMA Intern Med. 2019;179(9):1285-1287. doi:10.1001/jamainternmed.2019.0907

This study reviews all articles from 9 specialty and 4 cross-specialty medical journals across a 10-year period to assess trends in authorship, first authorship, and last authorship among women.

Assessment of Strategies for Managing Expansion of Diagnosis Coding Using Risk-Adjustment Methods for Medicare Data

Abstract Full Text
JAMA Intern Med. 2019;179(9):1287-1290. doi:10.1001/jamainternmed.2019.1005

This study of 100% Medicare Inpatient Files assesses strategies for managing coding of comorbidities associated with hospitalization before and after Centers for Medicare & Medicaid coding changes.

Prescription Patterns of Family Members After Discontinued Opioid or Benzodiazepine Therapy of Users

Abstract Full Text
JAMA Intern Med. 2019;179(9):1290-1292. doi:10.1001/jamainternmed.2019.1047

This study uses data from a national database of privately insured individuals from 2007 to 2016 to examine first-prescription filling patterns exhibited by family members of high-volume users of opioids or benzodiazepine whose drug treatment has been discontinued.

Adoption of Digital Breast Tomosynthesis in Clinical Practice

Abstract Full Text
JAMA Intern Med. 2019;179(9):1292-1295. doi:10.1001/jamainternmed.2019.1058

This study uses administrative claims from an insurance database to examine adoption of digital breast tomosynthesis for cancer screening and describe regional patterns and sociodemographic characteristics associated with its use.

Association Between High Discharge Rates of Vulnerable Patients and Skilled Nursing Facility Copayments

Abstract Full Text
JAMA Intern Med. 2019;179(9):1296-1298. doi:10.1001/jamainternmed.2019.1209

This study uses data from the Centers for Medicare and Medicaid Services to investigate the association between Medicare copayment policies and discharge rates of vulnerable patients from skilled nursing facilities.

All-Cause and Cause-Specific Mortality Among Major League Baseball Players

Abstract Full Text
JAMA Intern Med. 2019;179(9):1298-1301. doi:10.1001/jamainternmed.2019.1218

This study assesses the all-cause and cause-specific mortality rates among Major League Baseball players compared with the general US male population.

Challenges in Clinical Electrocardiography

Arrhythmogenic Syncope in a Soldier First-Responder Reveals Channelopathy—Last Response for the First Responder?

Abstract Full Text
JAMA Intern Med. 2019;179(9):1278-1280. doi:10.1001/jamainternmed.2019.2484

This case report describes the echocardiographic findings of a military nurse in her 20s with vasovagal syncope.

Comment & Response

Unified Approach Needed to Implement Nutrition Support Services

Abstract Full Text
JAMA Intern Med. 2019;179(9):1302-1303. doi:10.1001/jamainternmed.2019.3188

Unified Approach Needed to Implement Nutrition Support Services—Reply

Abstract Full Text
JAMA Intern Med. 2019;179(9):1303. doi:10.1001/jamainternmed.2019.3193
Correction

Funder and Disclaimer Added

Abstract Full Text
free access
JAMA Intern Med. 2019;179(9):1303. doi:10.1001/jamainternmed.2019.3260

Correction to Number in Abstract

Abstract Full Text
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JAMA Intern Med. 2019;179(9):1303. doi:10.1001/jamainternmed.2019.3746

Error in References

Abstract Full Text
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JAMA Intern Med. 2019;179(9):1303. doi:10.1001/jamainternmed.2019.3935

Errors in Figure Headings

Abstract Full Text
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JAMA Intern Med. 2019;179(9):1303-1304. doi:10.1001/jamainternmed.2019.4091

Error in Title of Table 2 and Rewording of Conflict of interest Disclosures

Abstract Full Text
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JAMA Intern Med. 2019;179(9):1304. doi:10.1001/jamainternmed.2019.4281
JAMA Internal Medicine Patient Page

My Doctor Told Me I Have Fatty Liver—What Do I Need to Know?

Abstract Full Text
free access has audio
JAMA Intern Med. 2019;179(9):1308. doi:10.1001/jamainternmed.2019.1240

This Patient Page describes nonalcoholic fatty liver disease and strategies for its treatment.

JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
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JAMA Intern Med. 2019;179(9):1160. doi:10.1001/jamainternmed.2018.5512
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