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January 2022, Vol 182, No. 1, Pages 3-95

Perspective

Medical Mentoring—Critique Me, Please

Abstract Full Text
JAMA Intern Med. 2022;182(1):5-6. doi:10.1001/jamainternmed.2021.6742

This essay describes a medical student’s former training as a musician and his pursuit for the same level of professional evaluation as a physician in training.

Original Investigation

Risk of Fracture Among Older Adults With Primary Hyperparathyroidism Receiving Parathyroidectomy vs Nonoperative Management

Abstract Full Text
JAMA Intern Med. 2022;182(1):10-18. doi:10.1001/jamainternmed.2021.6437

This population-based, longitudinal cohort study of all Medicare beneficiaries with primary hyperparathyroidism compares the incidence of clinical fracture among older patients treated with parathyroidectomy vs nonoperative management.

Association of Self-reported COVID-19 Infection and SARS-CoV-2 Serology Test Results With Persistent Physical Symptoms Among French Adults During the COVID-19 Pandemic

Abstract Full Text
free access has active quiz has audio
JAMA Intern Med. 2022;182(1):19-25. doi:10.1001/jamainternmed.2021.6454

This cross-sectional study of individuals from the French CONSTANCES cohort assesses whether the belief in having been infected with SARS-CoV-2, having serological test–confirmed COVID-19 infection, or both are associated with persistent physical symptoms often attributed to long COVID in the general adult population.

Association of Social Support With Functional Outcomes in Older Adults Who Live Alone

Abstract Full Text
JAMA Intern Med. 2022;182(1):26-32. doi:10.1001/jamainternmed.2021.6588

This cohort study assesses whether identifiable support buffers the vulnerability of a health shock in older adults who live alone.

Time to Benefit of Bisphosphonate Therapy for the Prevention of Fractures Among Postmenopausal Women With Osteoporosis: A Meta-analysis of Randomized Clinical Trials

Abstract Full Text
JAMA Intern Med. 2022;182(1):33-41. doi:10.1001/jamainternmed.2021.6745

This meta-analysis uses data from randomized clinical trials to assess the time to benefit of bisphosphonate therapy for the prevention of nonvertebral fractures among postmenopausal women with osteoporosis.

Efficacy of Inhaled Ciclesonide for Outpatient Treatment of Adolescents and Adults With Symptomatic COVID-19: A Randomized Clinical Trial

Abstract Full Text
free access has active quiz
JAMA Intern Med. 2022;182(1):42-49. doi:10.1001/jamainternmed.2021.6759

This randomized clinical trial examines the efficacy of the inhaled steroid ciclesonide in reducing the time to alleviation of all COVID-19–related symptoms among nonhospitalized participants with symptomatic COVID-19 infection.

Safety and Outcomes of Midline Catheters vs Peripherally Inserted Central Catheters for Patients With Short-term Indications: A Multicenter Study

Abstract Full Text
JAMA Intern Med. 2022;182(1):50-58. doi:10.1001/jamainternmed.2021.6844

This cohort study compares outcomes of peripherally inserted central catheters vs midline catheters placed for patients with the indication of difficult vascular access or antibiotic therapy for 30 or fewer days.

Editorial

Parathyroidectomy in Elderly Individuals With Primary Hyperparathyroidism: To Operate or Not to Operate

Abstract Full Text
JAMA Intern Med. 2022;182(1):7-8. doi:10.1001/jamainternmed.2021.6816

FDA Regulation of Medical Devices—Moving Beyond the Horse and Buggy

Abstract Full Text
JAMA Intern Med. 2022;182(1):8-9. doi:10.1001/jamainternmed.2021.6633
Special Communication

Renewing the Call for Reforms to Medical Device Safety—The Case of Penumbra

Abstract Full Text
JAMA Intern Med. 2022;182(1):59-65. doi:10.1001/jamainternmed.2021.6626

This Special Communication presents JET 7 reperfusion catheter as a case study of the need to address the gaps in US medical device regulation identified by the Institute of Medicine in 2011.

Teachable Moment

Considering Cannabis Use in Differential Diagnosis: A Teachable Moment

Abstract Full Text
has active quiz
JAMA Intern Med. 2022;182(1):66-67. doi:10.1001/jamainternmed.2021.6901

This Teachable Moment describes why patients with unexplained gastrointestinal symptoms should be asked about cannabis use and how considering a diagnosis of cannabis hyperemesis and withdrawal may avoid recurrent emergency visits, imaging, and hospital admissions.

Research Letter

Comparison of Classification of Indications for Allogeneic and Autologous Transplant for Adults in ASTCT Guidelines and Evidence Available in Published Literature

Abstract Full Text
JAMA Intern Med. 2022;182(1):76-78. doi:10.1001/jamainternmed.2021.4826

This cross-sectional study quantifies the number of randomized clinical trials in the literature for each indication for stem cell transplantation by disease type and status.

Guaranteed Financial Incentives for COVID-19 Vaccination: A Pilot Program in North Carolina

Abstract Full Text
free access has active quiz
JAMA Intern Med. 2022;182(1):78-80. doi:10.1001/jamainternmed.2021.6170

This quasi-experimental study examines whether offering an incentive cash card to adults who receive or drive someone to receive their first dose of COVID-19 vaccine raises vaccination rates.

Age- and Sex-Specific Incidence of Cerebral Venous Sinus Thrombosis Associated With Ad26.COV2.S COVID-19 Vaccination

Abstract Full Text
free access has active quiz
JAMA Intern Med. 2022;182(1):80-83. doi:10.1001/jamainternmed.2021.6352

This cohort study compares the sex- and age-adjusted incidence of cerebral venous sinus thrombosis before the COVID-19 pandemic with that during the first 92 days after Ad26.COV2.S vaccination.

Payer-Specific Negotiated Prices for Prescription Drugs at Top-Performing US Hospitals

Abstract Full Text
JAMA Intern Med. 2022;182(1):83-86. doi:10.1001/jamainternmed.2021.6445

This cross-sectional study analyzes a group of top-performing hospitals to quantify drug pricing variation across insurers.

Clinically Undetectable Heart Sounds in Hospitalized Patients Undergoing Echocardiography

Abstract Full Text
JAMA Intern Med. 2022;182(1):86-87. doi:10.1001/jamainternmed.2021.6594

This cross-sectional study examines undetectable heart sounds in hospitalized patients who are undergoing echocardiography and evaluates the association between patient factors and missed valvular heart disease diagnoses.

Leading Causes of Death Among Adults Aged 25 to 44 Years by Race and Ethnicity in Texas During the COVID-19 Pandemic, March to December 2020

Abstract Full Text
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JAMA Intern Med. 2022;182(1):87-90. doi:10.1001/jamainternmed.2021.6734

This cohort study examines mortality data from Texas, a racially and ethnically diverse state, to better understand excess mortality among adults aged 25 to 44 years during early months of the COVID-19 pandemic.

Less Is More

Prevalence of Medications That May Raise Blood Pressure Among Adults With Hypertension in the United States

Abstract Full Text
JAMA Intern Med. 2022;182(1):90-93. doi:10.1001/jamainternmed.2021.6819

This cross-sectional study characterizes the prevalent use of medications that may raise BP and examine their associations with BP control and antihypertensive use.

Challenges in Clinical Electrocardiography

Recurrent Syncope in a Patient With Bifascicular Block

Abstract Full Text
JAMA Intern Med. 2022;182(1):68-69. doi:10.1001/jamainternmed.2021.6599

This case report presents a patient in their 60s with no cardiovascular history who presented to the emergency department with recurrent syncope and no reported seizure activity, chest pain, palpitations, or shortness of breath before syncope.

The Unknown Rhythms After Transcatheter Aortic Valve Replacement

Abstract Full Text
JAMA Intern Med. 2022;182(1):70-71. doi:10.1001/jamainternmed.2021.6636

This case report presents the electrocardiographic findings of a patient in their 90s with hypertension, dyslipidemia, and type 2 diabetes and suspected symptomatic aortic stenosis.

An Unusual Wide Complex Rhythm—What Is the Diagnosis?

Abstract Full Text
JAMA Intern Med. 2022;182(1):72-73. doi:10.1001/jamainternmed.2021.6778

This case report describes a Chinese woman in her 80s who was referred for a cardiac evaluation after results from an electrocardiogram showed a wide QRS complex.

Not All Electrocardiographic ST-Elevations Are Acute Coronary Occlusions

Abstract Full Text
JAMA Intern Med. 2022;182(1):74-75. doi:10.1001/jamainternmed.2021.6887

This case report discusses a patient who presented to the emergency department with complaints of nausea, vomiting, and malaise for 5 days, and an initial electrocardiogram showed an ectopic atrial rhythm with no other abnormality.

Comment & Response

Comparative Effectiveness of Sodium-Glucose Cotransporter 2 Inhibitors vs Sulfonylureas in Patients With Type 2 Diabetes

Abstract Full Text
JAMA Intern Med. 2022;182(1):93. doi:10.1001/jamainternmed.2021.6321

Comparative Effectiveness of Sodium-Glucose Cotransporter 2 Inhibitors vs Sulfonylureas in Patients With Type 2 Diabetes—Reply

Abstract Full Text
JAMA Intern Med. 2022;182(1):93-94. doi:10.1001/jamainternmed.2021.6334

Coffee Consumption and Risk of Adverse Outcomes

Abstract Full Text
JAMA Intern Med. 2022;182(1):94-95. doi:10.1001/jamainternmed.2021.6920

Coffee Consumption and Risk of Adverse Outcomes—Reply

Abstract Full Text
JAMA Intern Med. 2022;182(1):95. doi:10.1001/jamainternmed.2021.6923
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
free access
JAMA Intern Med. 2022;182(1):3. doi:10.1001/jamainternmed.2021.6057
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