Using Information Technology to Improve the Monitoring of Outpatient Prescribing | Clinical Pharmacy and Pharmacology | JAMA Internal Medicine | JAMA Network
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Research Letter
Mar 11, 2013

Using Information Technology to Improve the Monitoring of Outpatient Prescribing

Alan J. Forster, MD, MSc; Claudine Auger, PhD; for the ISTOP ADE Investigators
Author Affiliations

Author Affiliations: Performance Measurement, The Ottawa Hospital, Ottawa, Ontario, Canada (Dr Forster); Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa (Dr Forster); Department of Epidemiology and Community Medicine (Dr Forster) and Department of Medicine, Faculty of Medicine (Dr Forster), University of Ottawa, Ottawa; Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada (Dr Forster); Clinical and Health Informatics Research Group, Montreal, Ontario, Canada (Dr Auger); and Epidemiology and Biostatistics Department, Faculty of Medicine, McGill University, Montreal (Dr Auger).

JAMA Intern Med. 2013;173(5):382-384. doi:10.1001/jamainternmed.2013.2002

Adverse drug events (ADEs) and medication nonadherence are common and reduce the potential benefit of medications. Adverse drug events, defined as poor health outcomes caused by medications,1 occur in up to 25% of ambulatory care patients prescribed a medication.2Medication nonadherence, defined as patients not taking their medications as directed,3 can occur in 25% of new prescriptions.2,4,5 Improved monitoring and communication could reduce ADEs and nonadherence to minimize medication-associated problems.

We designed the ISTOP-ADE system (Figure), an information technology–based approach to monitor ambulatory patients receiving incident prescriptions. This system automatically called patients 3 and 17 days following a prescription and allowed patients to request a pharmacist phone call. The purpose of this study was to determine this approach's potential effectiveness.