Management of Antimicrobial Allergies by Infectious Diseases Physicians | Allergy and Clinical Immunology | JAMA Internal Medicine | JAMA Network
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Research Letter
July 22, 2013

Management of Antimicrobial Allergies by Infectious Diseases Physicians

Author Affiliations
  • 1Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida
  • 2Carver College of Medicine, University of Iowa, Iowa City
  • 3College of Public Health, University of Iowa, Iowa City
JAMA Intern Med. 2013;173(14):1376-1378. doi:10.1001/jamainternmed.2013.6480

Misconceptions about true antimicrobial allergy may result in less effective, more expensive therapy and adverse outcomes.1,2 Correctly identifying allergies could significantly reduce the immediate and direct risks of drug-related adverse events.3 For example, 9 of 10 patients who reported an allergy to penicillin were, in fact, not, when evaluated by skin testing (ST).4 To appropriately use first-line agents, it is important to determine if the patient truly has an antimicrobial allergy. Such efforts could contribute to better antimicrobial stewardship.

To better understand physicians’ perceptions and knowledge about allergy, a 10-item survey was e-mailed to Infectious Diseases Society of America (IDSA) Emerging Infections Network (EIN) members, a sentinel network of infectious diseases (ID) physicians across North America. Data were analyzed using SAS version 9.3 statistical software (SAS Institute Inc).