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Spinal augmentation is the injection of bone cement into the collapsed vertebral body for treatment of osteoporotic vertebral fractures. In this study of spinal augmentation compared with conservative therapy, spinal augmentation was no more effective than conservative therapy in reducing the rate of major complications or mortality but resulted in higher rates of hospitalization and admission to the intensive care unit and to skilled nursing facilities. Based on the findings of no benefit from this invasive procedure, and definite harms including higher rates of hospitalization and other risks, we have designated this study by McCullough et al as Less Is More.
Published Online: July 8, 2013. doi:10.1001/jamainternmed.2013.6761.
Grady D. Spinal Augmentation for Vertebral Fracture. JAMA Intern Med. 2013;173(16):1523. doi:10.1001/jamainternmed.2013.6761