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April 27, 1998

Treatment of Helicobacter pylori Infection

Author Affiliations

From the Department of Gastroenterology, Georgetown University Medical Center, Washington, DC.

Arch Intern Med. 1998;158(8):842-851. doi:10.1001/archinte.158.8.842

Since acceptance of the association between Helicobacter pylori and peptic ulcer disease, eradication of H pylori has become the standard of care in the treatment of peptic ulcer disease. Unfortunately, eradication therapy is no easy task, especially when one is faced with a myriad of drug combinations with varying degrees of efficacy and tolerability. The following is a review of the literature regarding the drugs and drug combinations used to eradicate H pylori and their effectiveness both as single agents and in combination.