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In This Issue of JAMA Internal Medicine
September 2015


JAMA Intern Med. 2015;175(9):1433-1435. doi:10.1001/jamainternmed.2014.5084

The Mini-Mental State Examination (MMSE) is the proprietary instrument for dementia screening. Tsoi and colleagues performed a meta-analysis on 149 diagnostic studies with over 49 000 subjects to compare the diagnostic accuracy between the MMSE and 10 other screening tests. Results showed screening tests other than the MMSE were comparably effective, easier to perform, and available for little or no cost. These findings support the increasing use of other tests for dementia screening.

Invited Commentary

Cognitive behavioral therapy for insomnia (CBT-I) is the current gold standard nonpharmacological treatment for insomnia disorders. To examine the efficacy of CBT-I for insomnia comorbid with psychiatric and/or medical conditions, Wu and colleagues conducted a meta-analysis of 37 randomized clinical trials with an adult patient population meeting criteria for insomnia and a co-occurring condition and found medium to large improvements in sleep efficiency, sleep onset latency, wake after sleep onset, and sleep quality. There were also overall small improvements in comorbid outcomes, which were greater in psychiatric populations than in medical populations. Wu and colleagues concluded that CBT-I is effective for improving insomnia symptoms and sleep parameters for patients with comorbid insomnia.