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Figure 1.  Rates of Measurement of B-type Natriuretic Peptide (BNP) and Troponin Levels
Rates of Measurement of B-type Natriuretic Peptide (BNP) and Troponin Levels

Recommendations were released in March 2014 for measurement of BNP levels in the workup of acute dyspnea and of troponin levels in the workup of acute chest pain. Use of both tests declined significantly (P < .001).

Figure 2.  Rates of Measurement of Amylase, Creatine Kinase (CK), and Lactic Dehydrogenase (LDH) Levels
Rates of Measurement of Amylase, Creatine Kinase (CK), and Lactic Dehydrogenase (LDH) Levels

Recommendations were released in July 2014 for unbundling of a panel chemistry workup. A significant reduction in routine testing of LDH, amylase, and CK levels resulted (P < .001).

1.
Cassel  CK, Guest  JA.  Choosing Wisely: helping physicians and patients make smart decisions about their care.  JAMA. 2012;307(17):1801-1802.PubMedGoogle ScholarCrossref
2.
Mueller  C, Scholer  A, Laule-Kilian  K,  et al.  Use of B-type natriuretic peptide in the evaluation and management of acute dyspnea.  N Engl J Med. 2004;350(7):647-654.PubMedGoogle ScholarCrossref
3.
Vegting  IL, van Beneden  M, Kramer  MH, Thijs  A, Kostense  PJ, Nanayakkara  PW.  How to save costs by reducing unnecessary testing: lean thinking in clinical practice.  Eur J Intern Med. 2012;23(1):70-75.PubMedGoogle ScholarCrossref
4.
Corson  AH, Fan  VS, White  T,  et al.  A multifaceted hospitalist quality improvement intervention: decreased frequency of common labs.  J Hosp Med. 2015;10(6):390-395.PubMedGoogle ScholarCrossref
5.
Gupta  S, Detsky  AS.  Development of Choosing Wisely recommendations for an inpatient internal medicine service.  JAMA Intern Med. 2015;175(4):642-644.PubMedGoogle ScholarCrossref
6.
Selby  K, Gaspoz  JM, Rodondi  N,  et al.  Creating a list of low-value health care activities in Swiss primary care.  JAMA Intern Med. 2015;175(4):640-642.PubMedGoogle ScholarCrossref
Research Letter
March 2016

Hospital Care Efficiency and the SMART (Specific, Measurable, Agreed, Required, and Timely) Medicine Initiative

Author Affiliations
  • 1Division of Internal Medicine, Rambam Health Care Campus, Haifa, Israel
  • 2Intel Electronics, Ltd, Haifa, Israel
JAMA Intern Med. 2016;176(3):398-399. doi:10.1001/jamainternmed.2015.7705

A considerable proportion of hospital resources is spent on various laboratory and imaging tests. This reality presents a significant challenge to medical teams with regard to intelligent and efficient use of these tools during hospital care.1 The SMART (Specific, Measurable, Agreed, Required, and Timely) Medicine initiative, conducted by the Division of Internal Medicine at the Rambam Health Care Campus, aims to improve the efficiency of medical investigations by making the use of diagnostic tools more precise, focused, and based on the clinical findings.

Methods

The project was a multifaceted medical education campaign managed by a group of senior physicians (including D.B.-H., A.Y., and J.K.), with continuous and systematic monitoring and feedback. The group met monthly to discuss issues from the practice of internal medicine with a content expert and Intel engineers (V.B. and N.G.) who volunteered as part of a nationwide community involvement program. At the end of each meeting, the forum wrote up a set of recommendations that were communicated to all physicians in the Division of Internal Medicine through various channels. The impact of the initiative was continuously measured by quantifiable data related to blood and imaging tests, and a defined set of measurements was reported to the staff as monthly feedback. The need for study approval was waived by the institutional review board of the Rambam Health Care Campus.

Results

Various topics were discussed during 2014, and a set of recommendations for common laboratory tests and other diagnostic tests was compiled by the forum. For example, we agreed that measurement of B-type natriuretic peptide levels as part of the workup for acute dyspnea should not be included in cases with an unequivocal diagnosis of acute left heart failure or with a more likely alternative diagnosis.2 Proper use of troponin level measurement in the workup of patients presenting with chest pain and recommendations for avoiding unnecessary repeated testing represented another example. Use of both tests was significantly reduced (Figure 1). Another issue discussed by our forum was routine (and unnecessary) blood tests. We found that unbundling panel chemistry tests reduced the use of routine measurement of lactic dehydrogenase, creatine kinase, and amylase levels by more than 50% (Figure 2). The number of tests ordered for C-reactive protein, hemoglobin A1c, and thyrotropin levels was also significantly reduced. During the first year of the project, we achieved a 20% reduction in the total number of laboratory tests performed, resulting in a savings of $250 000. In addition, the laboratory turnaround time from sample receipt to results dispatch was reduced.

Discussion

We have presented an example of successful development of a method for the use of diagnostic tools for a specific topic list, inspired by the US Choosing Wisely campaign,1 in an individual hospital. Our initiative was implemented through an educational model that included systematic monitoring and feedback. Although the selected topics may not be generalizable beyond the scope of our division’s practice, the guiding principles of the method can be applied in other settings. In recent years, many studies dealing with cost-effectiveness and reduction of low-value health care activities by different types of interventions have been published.3-6 However, several elements make our initiative unique. First, our recommendations are based on thorough discussion of the medical investigation process required for different scenarios in internal medicine. Second, collaboration with Intel enabled thorough data analysis with high-quality feedback. Last, SMART Medicine has led to a substantial change in the patterns of medical thinking regarding the use of diagnostic tests among our medical personnel; therefore, we believe that its impact will be maintained.

In addition to cost-effectiveness, SMART Medicine has contributed to patient safety by avoiding unnecessary exposure to radiation, contrast media, incidental findings, and false-positive results. In summary, SMART Medicine represents a milestone in the development and implementation of a defined method for wiser use of diagnostic tools.

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Article Information

Corresponding Author: Gidon Berger, MD, Division of Internal Medicine, Rambam Health Care Campus, Haaliyah Hashnia, Haifa 31096, Israel (g_berger@rambam.health.gov.il).

Published Online: February 1, 2016. doi:10.1001/jamainternmed.2015.7705.

Author Contributions: Ms Belsky and Dr Berger had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

Study concept and design: All authors.

Acquisition, analysis, or interpretation of data: Zalts, Belsky, Grushko, Berger.

Drafting of the manuscript: Yahia, Khateeb, Belsky, Grushko, Berger.

Critical revision of the manuscript for important intellectual content: Zalts, Ben-Hur, Khateeb, Belsky, Berger.

Statistical analysis: Belsky, Grushko.

Administrative, technical, or material support: Yahia, Khateeb, Grushko, Berger.

Study supervision: Zalts, Yahia, Khateeb, Belsky, Berger.

Conflict of Interest Disclosures: None reported.

Additional Contributions: Anees Mussalam, MD, Bella Smolin, MD, Rabea Sheikh-Muhamad, MD, and Matti Waterman, MD, Division of Internal Medicine, Rambam Health Care Campus, participated as forum members. Liz Ghazi, BSc, Intel Electronics, Ltd, provided technical support. Deborah Hemstreet, MA, Rambam Health Care Campus, assisted in editing the manuscript. None of them received financial compensation for their role.

References
1.
Cassel  CK, Guest  JA.  Choosing Wisely: helping physicians and patients make smart decisions about their care.  JAMA. 2012;307(17):1801-1802.PubMedGoogle ScholarCrossref
2.
Mueller  C, Scholer  A, Laule-Kilian  K,  et al.  Use of B-type natriuretic peptide in the evaluation and management of acute dyspnea.  N Engl J Med. 2004;350(7):647-654.PubMedGoogle ScholarCrossref
3.
Vegting  IL, van Beneden  M, Kramer  MH, Thijs  A, Kostense  PJ, Nanayakkara  PW.  How to save costs by reducing unnecessary testing: lean thinking in clinical practice.  Eur J Intern Med. 2012;23(1):70-75.PubMedGoogle ScholarCrossref
4.
Corson  AH, Fan  VS, White  T,  et al.  A multifaceted hospitalist quality improvement intervention: decreased frequency of common labs.  J Hosp Med. 2015;10(6):390-395.PubMedGoogle ScholarCrossref
5.
Gupta  S, Detsky  AS.  Development of Choosing Wisely recommendations for an inpatient internal medicine service.  JAMA Intern Med. 2015;175(4):642-644.PubMedGoogle ScholarCrossref
6.
Selby  K, Gaspoz  JM, Rodondi  N,  et al.  Creating a list of low-value health care activities in Swiss primary care.  JAMA Intern Med. 2015;175(4):640-642.PubMedGoogle ScholarCrossref
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