Evaluation of a Trainee-Led Project to Reduce Inappropriate Proton Pump Inhibitor Infusion in Patients With Upper Gastrointestinal Bleeding: Skip the Drips | Clinical Pharmacy and Pharmacology | JAMA Internal Medicine | JAMA Network
[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 18.207.108.182. Please contact the publisher to request reinstatement.
[Skip to Navigation Landing]
Research Letter
Less Is More
November 2017

Evaluation of a Trainee-Led Project to Reduce Inappropriate Proton Pump Inhibitor Infusion in Patients With Upper Gastrointestinal Bleeding: Skip the Drips

Author Affiliations
  • 1Section of Gastroenterology, Department of Medicine, University of Chicago, Chicago, Illinois
  • 2Division of Cardiology, Department of Medicine, University of California, Los Angeles
  • 3Graduate Program in Health Administration and Policy, University of Chicago, Chicago, Illinois
  • 4Pharmacy Services, University of Chicago Medical Center, Chicago, Illinois
  • 5Section of General Internal Medicine, Department of Medicine, University of Chicago, Chicago, Illinois
JAMA Intern Med. 2017;177(11):1687-1689. doi:10.1001/jamainternmed.2017.4851

Continuous infusion of proton pump inhibitors (PPIs) is recommended in patients with upper gastrointestinal bleeding (UGIB) for specific situations, such as before endoscopic identification of ulcers with high-risk features1-4 (Box). Unfortunately, PPI infusions may be continued for 72 hours without indication.2,5 Reducing the overuse of these infusions is important because, in addition to increasing the length of stay and cost, PPI overuse is associated with various complications.6 In July 2015, a fellow- and resident-led intervention was initiated with the goals of decreasing the inappropriate use of PPI infusions in patients with UGIB and promoting evidence-based care at lower costs for these patients.

×