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Kim et al estimated radiation doses and associated cancer risks from coronary artery calcification screening with multidetector computed tomography, according to patient age, frequency of screening, and scan protocol. The radiation dose from a single coronary artery calcification computed tomographic scan varied more than 10-fold (effective dose range, 0.8-10.5 mSv) depending on the protocol. Assuming screening every 5 years from the age of 45 to 75 years for men and from age 55 to 75 years for women, the estimated excess lifetime cancer risk using the median dose of 2.3 mSv (range, 0.8-10.5 mSv) was 42 cases per 100 000 men (range, 14-200 cases) and 62 cases per 100 000 women (range, 21-300 cases). These radiation risk estimates can be compared with potential benefits from screening, when such estimates are available. Doses and therefore risks can be minimized by using optimized protocols.
In This Issue of Archives of Internal Medicine. Arch Intern Med. 2009;169(13):1179. doi:10.1001/archinternmed.2009.174
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