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In This Issue of Archives of Internal Medicine
January 10, 2005

In This Issue of Archives of Internal Medicine

Arch Intern Med. 2005;165(1):12. doi:10.1001/archinte.165.1.12

In a population-based retrospective cohort study of older adults hospitalized for newly diagnosed heart failure, the composite outcome of subsequent death, acute myocardial infarction, or stroke occurred in 217 of 1146 new statin recipients (13.6 per 100 person-years) vs 12 299 of 27 682 nonrecipients (21.8 per 100 person-years), which is equivalent to an adjusted hazard ratio of 0.72. The principal benefit from statins was related to a reduction in all-cause mortality (adjusted HR, 0.67). Statin use is associated with a lower risk of death among seniors newly diagnosed as having congestive heart failure.

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Some patients with cryoglobulinemic syndrome develop frank non-Hodgkin lymphoma (NHL), but the incidence and timing of this event are still poorly defined. This study retrospectively assessed the cumulative incidence and characteristics of NHL in a large series of patients with cryoglobulinemia syndrome observed in 11 centers belonging to the Italian Group for the Study of Cryoglobulinemia. The overall incidence of NHL after the diagnosis of cryoglobulinemia syndrome in 1255 hepatitis C virus–positive patients followed up for 8928 person-years was about 35 times higher than that in the normal population and was still 12 times higher considering only the aggressive NHL histotypes.