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Article
September 1960

Variation of Staphylococcus (Micrococcus Pyogenes)

Author Affiliations
Philadelphia
Arch Intern Med. 1960;106(3):341-344. doi:10.1001/archinte.1960.03820030029006
Abstract

Staphylococcus now exceeds other Grampositive cocci as an important cause of disease and death, yet basic information of its ecology, pathogenesis, and immune relationships is incomplete.1 Intensive studies of its dissociative pattern had not been made in contrast with those of Pneumococcus and Streptococcus whose main colonial variant forms are known as mucoid (M), smooth (S), and rough (R). Besides, transformation from one serologic type to another, each with its M, S, and R forms, can be induced among pneumococci and takes place spontaneously in tetragena.2 However, there is little evidence of the implication of these changes in the origin or recovery from infection.

Because Staphylococcus is unique among pathogenic cocci in its ability to become resistant to antimicrobials, this study was made to fill in missing data about its dissociative behavior and to see if microbic variation plays a role in the development of drug-resistance and in

References
1.
Mudd, S.:  Staphylococcic Infections in the Hospital and Community ,  J.A.M.A. 166:1177-1178 ( (March 8) ) 1958.Crossref
2.
Reimann, H. A.:  The Significance of Bacterial Variation: V. Micrococcus Tetragenous Infection ,  J. Bact. 33:513-523 ( (May) ) 1936.
3.
Goslings, W. R. O., and Büchli, K.:  Nasal Carrier Rate of Antibiotic-Resistant Staphylococci: Influence of Hospitalization on Carrier Rate in Patients and Their Household Contacts ,  A.M.A. Arch. Int. Med. 102:691-715 ( (Nov.) ) 1958.Crossref
4.
Smith, I. M.; Beals, P. D.; Kingsbury, K. R., and Hasenclever, H. F.:  Observations on Staphylococcus Albus Septicemia in Mice and Men ,  A.M.A. Arch. Int. Med. 102:375-388 ( (Sept.) ) 1958.Crossref
5.
Reimann, H. A.:  Transformation and Culture Phase Dissociation of Staphylococcus (Micrococcus Pyogenes) ,  Proc. Soc. Exper. Biol. & Med. 96:411-415 ( (Nov.) ) 1957.
6.
Pinner, M., and Voldrich, M. J.:  Derivation of Staphylococcus Albus, Citreus and Roseus from Staphylococcus Aureus ,  J. Infect. Dis. 50: 185-202 ( (June-July) ) 1932.
7.
Byatt, P. H.; Jann, G. I., and Salle, A. J.:  Variations in Pigment Production in Staphylococcus Aureus ,  J. Bact. 55:787-792 ( (June) ) 1948.
8.
Suzue, G., and Tanaka, S.:  Carotenogenesis and Resistance of Micrococcus Pyogenes to Tetracyclines ,  Science 129:1359-1360 ( (May 15) ) 1959.
9.
Bryson, V.:  Genetics of Antimicrobial Resistance ,  Ann. New York Acad. Sci. 65:161-168 ( (Aug. 31) ) 1956.
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