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August 1966

Retroperitoneal Malignant Schwannoma and Chylous Effusions

Author Affiliations


From the Pathology Department of University Hospital, and Boston University Medical School, Boston.

Arch Intern Med. 1966;118(2):168-171. doi:10.1001/archinte.1966.00290140072015

PRIMARY retroperitoneal malignancies and malignant schwannomas are rare. Their occurrence together has been reported in only 14 patients. Stout1 reviewed 137 malignant tumors of peripheral nerves, and six of these tumors were located in the retroperitoneal area. Ackerman2 describes a retroperitoneal malignant schwannoma and mentions three others tabulated by Stout in a series from Columbia University. Carpenter and Kernohan3 found four cases of malignant schwannomas arising in the retroperitoneal area, in a study of the Mayo Clinic material over a 33-year period, which excluded cases of von Recklinghausen's disease.

Chylous effusions are generally associated with trauma or neoplasms. The neoplasms most frequently encountered causing chylous effusions are metastatic carcinomas, lymphomas, and rarely sarcomas, as indicated in the Table.4-7 Nix 7 reviewed 302 cases of chylous effusions, 84 of which were caused by neoplasms. Wallis and Scholberg4 enumerated 233 cases of chylous effusions of which 81 were due to malignancies, six

Stout, A.P.:  The Malignant Tumors of the Peripheral Nerves ,  Amer J Cancer 25:1, 1935.
Ackerman, L.V.:  "Tumors of the Retroperitoneum,"  in  Atlas of Tumor Pathology , Washington, DC: Armed Forces Institute of Pathology, section 6, fascicle 24.
Carpenter, W.B., and Kernohan, J.W.:  Retroperitoneal Ganglioneuromas and Neurofibromas: A Clinical Pathologic Study ,  Cancer 16:788, 1963.Crossref
Wallis, R.L.M., and Scholberg, H.A.:  On Chylous and Pseudochylous Ascites ,  Quart J Med 4:153, 1910.
Bower, G.C.:  Chylothorax: Observations in 20 Cases ,  Dis Chest 46:464, 1964.Crossref
Jahsman, W.E.:  Chylothorax: Brief Review of Literature. Report of Three Nontraumatic Cases ,  Ann Intern Med 21:669, 1944.Crossref
Nix, J.T., et al:  Chylothorax and Chylous Ascites: A Study of 302 Cases ,  Amer J Gastroent 28:40, 1957.
Stout, A.P.:  "Tumors of the Peripheral Nervous System,"  in  Atlas of Tumor Pathology , Washington, DC: Armed Forces Institute of Pathology, section 2, fascicle 6, p 28.
Stout, A.P.:  Tumors of the Peripheral Nervous System ,  J Missouri Med Assoc 46:255, 1949.