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August 1978

Familial Myopathy: Exacerbation by Hypokalemia Associated With Colonic Polyp

Author Affiliations

From the Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas.

Arch Intern Med. 1978;138(8):1283-1284. doi:10.1001/archinte.1978.03630330081025

A patient with Charcot-Marie-Tooth disease developed profuse mucinous diarrhea and severe potassium depletion. After two weeks, her muscle weakness grew worse, rhabdomyolysis occurred, and kaliopenic nephropathy was suspected. The patient's diarrhea ended abruptly after a single tubular adenomatous polyp was removed from her colon. Her metabolic status became normal and remained normal six weeks after transcolonic polypectomy.

(Arch Intern Med 138:1283-1284, 1978)

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Levitan R:  Colonic villous adenoma and fecal loss of sodium .  Gastroenterology 50:301-302, 1966.
Spiro HM:  Clinical Gastroenterology , ed 2. New York, Macmillan Co, 1977, p 850.