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Article
December 1914

POSTANESTHETIC GLYCOSURIA AS INFLUENCED BY DIET, BODY TEMPERATURE AND PURITY OF THE ETHER

Author Affiliations

CHICAGO; PHILADELPHIA

From the Laboratories of Physiological-Chemistry of Jefferson Medical College and the University of Illinois.

Arch Intern Med (Chic). 1914;XIV(6):779-785. doi:10.1001/archinte.1914.00070180012002
Abstract

In 1904 one of us1 reported the occurrence of glycosuria when meat-fed or fasting dogs were subjected to ether anesthesia for varying periods of time. In the case of the meat-fed animals the percentage of dextrose in the urine fraction first voided after anesthesia ranged from 1.32 per cent. to 6.94 per cent. In the case of the fasting dogs the percentage ranged from a negative test to 0.52 per cent.2 In 1905 Seelig3 confirmed these findings. At this time (1904-6) all ethers used for purposes of anesthesia contained aldehyd and other impurities. Recently Prof. Charles Baskerville has succeeded in purifying ethers,4 and it was he who suggested that we investigate the relationship of this purified or so-called "dehydrated" ether to postanesthetic glycosuria.5

Two other phases of the glycosuria question were incorporated with the study of the glycosuria-producing properties of the

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We wish to thank Professor Baskerville and Squibb & Sons for their kindness in furnishing the ether used in these experiments.
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