Matlock and coauthors conducted a cross-sectional study of hospital-level variation in the use of dual-chamber implantable cardioverter defibrillator (ICDs) across the United States. Multivariate hierarchical logistic regression was used to explore patient, health care provider, and physician factors related to the use of a dual-chamber device.
Emergency department use by newly insured vs continuously insured adults and by newly uninsured vs continuously uninsured adults are compared by Lowe et al. An accompanying editorial by Katz discusses other options to emergency department use to avoid using the emergency department as a health care default.
The association of antipsychotic agent use with the risk of acute myocardial infarction was investigated by Pariente et al. An Invited Critique by Gill and Seitz accompanies this article.
De Luca et al, for the DESERT Cooperation, performed a meta-analysis using individual patient data to evaluate the long-term safety and effectiveness of drug-eluting stents compared with bare-metal stents in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction. In an 694, Brophy discusses the findings of the meta-analysis.
A meta-analysis of safety and efficacy outcomes in patients with atrial fibrillation treated with warfarin for stroke prevention in large contemporary randomized controlled trials was performed by Agarwal et al. Singer and Go comment on these findings in the Invited Critique.
Prasad and Vandross propose that the bar for cardiovascular primary prevention has been raised and consider the implications of this proposal.
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