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May 2014, Vol 174, No. 5, Pages 657-828

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
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JAMA Intern Med. 2014;174(5):657-659. doi:10.1001/jamainternmed.2013.10650
Viewpoint

Why Does Antimicrobial Overuse in Hospitalized Patients Persist?

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JAMA Intern Med. 2014;174(5):661-662. doi:10.1001/jamainternmed.2014.897
Inside Story

Full Circle

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JAMA Intern Med. 2014;174(5):663-664. doi:10.1001/jamainternmed.2014.181

Less Is More

False-Positive Results From a Diagnostic Colonoscopy: A Teachable Moment

Abstract Full Text
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JAMA Intern Med. 2014;174(5):665-666. doi:10.1001/jamainternmed.2014.184

Less Is More

Questioning Protocol

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JAMA Intern Med. 2014;174(5):667. doi:10.1001/jamainternmed.2014.107
Editorial

Informed Consent in Randomized Quality Improvement Trials: A Critical Barrier for Learning Health Systems

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JAMA Intern Med. 2014;174(5):668-670. doi:10.1001/jamainternmed.2013.13297
Original Investigation

Proactive Tobacco Treatment and Population-Level Cessation: A Pragmatic Randomized Clinical Trial

Abstract Full Text
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JAMA Intern Med. 2014;174(5):671-677. doi:10.1001/jamainternmed.2014.177

Fu and colleagues assess the effect of a proactive, population-based tobacco cessation care model on use of evidence-based tobacco cessation treatments and on population-level smoking cessation rates.

Less Is More

National Estimates of Insulin-Related Hypoglycemia and Errors Leading to Emergency Department Visits and Hospitalizations

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JAMA Intern Med. 2014;174(5):678-686. doi:10.1001/jamainternmed.2014.136

Geller et al describe the US burden, rates, and characteristics of emergency department visits and emergency hospitalizations for insulin-related hypoglycemia and errors. See also the invited commentary by Lee.

Nonleg Venous Thrombosis in Critically Ill Adults: A Nested Prospective Cohort Study

Abstract Full Text
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JAMA Intern Med. 2014;174(5):689-696. doi:10.1001/jamainternmed.2014.169

Lamontagne and colleagues describe the frequency, anatomical location, risk factors, management, and consequences of nonleg deep venous thromboses in a large cohort of medical-surgical critically ill adults. Maynard provides an Invited Commentary.

Trends in Anemia Care in Older Patients Approaching End-Stage Renal Disease in the United States (1995-2010)

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JAMA Intern Med. 2014;174(5):699-707. doi:10.1001/jamainternmed.2014.87

Winkelmayer et al determine the trends in anemia treatment received by Medicare beneficiaries approaching end-stage renal disease. Coyne provides an Invited Commentary.

Clinical Questions Raised by Clinicians at the Point of Care: A Systematic Review

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JAMA Intern Med. 2014;174(5):710-718. doi:10.1001/jamainternmed.2014.368

Del Fiol et al systematically review studies that examined the questions that clinicians raise in the context of patient care decision making. See also the invited commentary by Carnahan.

Optimization of Human Immunodeficiency Virus Treatment During Incarceration: Viral Suppression at the Prison Gate

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JAMA Intern Med. 2014;174(5):721-729. doi:10.1001/jamainternmed.2014.601

Meyer et al evaluate human immunodeficiency virus (HIV) treatment outcomes throughout incarceration, including jail and prison. Puisis provides an Invited Commentary on the progress of HIV care in prisons.

Expression of HLA Class I Antigen, Aspirin Use, and Survival After a Diagnosis of Colon Cancer

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JAMA Intern Med. 2014;174(5):732-739. doi:10.1001/jamainternmed.2014.511

Reimers et al examine whether survival benefit associated with low-dose aspirin use after a diagnosis of colorectal cancer might depend on HLA class I antigen expression. Neugut provides an invited commentary.

Continuity and the Costs of Care for Chronic Disease

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JAMA Intern Med. 2014;174(5):742-748. doi:10.1001/jamainternmed.2014.245

Hussey et al measure the association between care continuity, costs, and rates of hospitalizations, emergency department visits, and complications for Medicare beneficiaries with chronic disease. See the invited commentary by Chen and Ayanian.

Reappraisal of Routine Oral Care With Chlorhexidine Gluconate for Patients Receiving Mechanical Ventilation: Systematic Review and Meta-Analysis

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JAMA Intern Med. 2014;174(5):751-761. doi:10.1001/jamainternmed.2014.359

Klompas et al evaluate the impact of routine oral care with chlorhexidine gluconate on patient-centered outcomes in patients undergoing mechanical ventilation. Bonten provides an Invited Commentary.

Effect of Long-Chain ω-3 Fatty Acids and Lutein + Zeaxanthin Supplements on Cardiovascular Outcomes: Results of the Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial

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JAMA Intern Med. 2014;174(5):763-771. doi:10.1001/jamainternmed.2014.328

This article from the Writing Group for the AREDS2 Research Group determines if supplementing the diet with long-chain ω-3 polyunsaturated fatty acids or with macular xanthophylls results in a reduced rate of cardiovascular disease. Rizos and Ntzani provide an Invited Commentary.

Effect of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on All-Cause Mortality, Cardiovascular Deaths, and Cardiovascular Events in Patients With Diabetes Mellitus: A Meta-analysis

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JAMA Intern Med. 2014;174(5):773-785. doi:10.1001/jamainternmed.2014.348

Cheng et al conduct a meta-analysis to separately evaluate the effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on all-cause mortality, cardiovascular deaths, and major cardiovascular events in patients with diabetes mellitus.

Effect of Hospitalist Workload on the Quality and Efficiency of Care

Abstract Full Text
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JAMA Intern Med. 2014;174(5):786-793. doi:10.1001/jamainternmed.2014.300

Elliott et al examine the association between hospitalist workload and the efficiency and quality of inpatient care. See the invited commentary by Wachter.

High-Risk Use by Patients Prescribed Opioids for Pain and Its Role in Overdose Deaths

Abstract Full Text
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JAMA Intern Med. 2014;174(5):796-801. doi:10.1001/jamainternmed.2013.12711

Baumblatt and coauthors assess the contribution of certain opioid-prescribing patterns to the risk of overdose death.

Invited Commentary

So Much Insulin, So Much Hypoglycemia

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JAMA Intern Med. 2014;174(5):686-688. doi:10.1001/jamainternmed.2013.13307

Upper Extremity Deep Vein Thrombosis: A Call to Arms

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JAMA Intern Med. 2014;174(5):696-698. doi:10.1001/jamainternmed.2013.14014

Anemia in Chronic Kidney Disease: Treating the Numbers, Not the Patients

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JAMA Intern Med. 2014;174(5):708-709. doi:10.1001/jamainternmed.2013.13305

Water, Water, Everywhere, and Not a Drop to Drink

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JAMA Intern Med. 2014;174(5):719-720. doi:10.1001/jamainternmed.2014.1

Progress in Human Immunodeficiency Virus Care in Prisons: Still Room for Improvement?

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JAMA Intern Med. 2014;174(5):730-731. doi:10.1001/jamainternmed.2014.521

Aspirin as Adjuvant Therapy for Stage III Colon Cancer: Standard of Care?

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JAMA Intern Med. 2014;174(5):739-741. doi:10.1001/jamainternmed.2013.14544

Care Continuity and Care Coordination: What Counts?

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JAMA Intern Med. 2014;174(5):749-750. doi:10.1001/jamainternmed.2013.14331

Chlorhexidine-Based Oral Care and Ventilator-Associated Pneumonia: The Devil in Disguise?

Abstract Full Text
JAMA Intern Med. 2014;174(5):761-762. doi:10.1001/jamainternmed.2013.14017

ω-3 Fatty Acids and Lutein + Zeaxanthin Supplementation for the Prevention of Cardiovascular Disease

Abstract Full Text
JAMA Intern Med. 2014;174(5):771-772. doi:10.1001/jamainternmed.2013.13734

Hospitalist Workload: The Search for the Magic Number

Abstract Full Text
JAMA Intern Med. 2014;174(5):794-795. doi:10.1001/jamainternmed.2014.18
Editor's Note

If Only Electronic Cigarettes Were Effective Smoking Cessation Devices

Abstract Full Text
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JAMA Intern Med. 2014;174(5):813-814. doi:10.1001/jamainternmed.2014.167

Multimorbidity, Guidelines, and Clinical Inertia

Abstract Full Text
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JAMA Intern Med. 2014;174(5):819. doi:10.1001/jamainternmed.2013.14406

Coping With Headaches

Abstract Full Text
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JAMA Intern Med. 2014;174(5):821-822. doi:10.1001/jamainternmed.2014.33
Research Letter

Sources of Prescription Opioid Pain Relievers by Frequency of Past-Year Nonmedical Use: United States, 2008-2011

Abstract Full Text
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JAMA Intern Med. 2014;174(5):802-803. doi:10.1001/jamainternmed.2013.12809

Blood Culture Use in the Emergency Department in Patients Hospitalized for Community-Acquired Pneumonia

Abstract Full Text
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JAMA Intern Med. 2014;174(5):803-806. doi:10.1001/jamainternmed.2013.13808

Representation of Women as Authors of Collaborative Cancer Clinical Trials

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JAMA Intern Med. 2014;174(5):806-808. doi:10.1001/jamainternmed.2014.250

Menthol Cigarette Use and Stroke Risk Among US Smokers: A Critical Reappraisal

Abstract Full Text
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JAMA Intern Med. 2014;174(5):808-809. doi:10.1001/jamainternmed.2013.9600

End-Stage Renal Disease From Human Immunodeficiency Virus–Associated Nephropathy in the United States, 2001 Through 2010

Abstract Full Text
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JAMA Intern Med. 2014;174(5):809-811. doi:10.1001/jamainternmed.2014.29

A Longitudinal Analysis of Electronic Cigarette Use and Smoking Cessation

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JAMA Intern Med. 2014;174(5):812-813. doi:10.1001/jamainternmed.2014.187

Do Physicians Spend Less Time With Patients in Contact Isolation?A Time-Motion Study of Internal Medicine Interns

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JAMA Intern Med. 2014;174(5):814-815. doi:10.1001/jamainternmed.2014.537

Predictors of Mortality and Major In-Hospital Adverse Events Associated With Electrophysiology Catheter Ablation

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JAMA Intern Med. 2014;174(5):815-817. doi:10.1001/jamainternmed.2014.415

Medical Conspiracy Theories and Health Behaviors in the United States

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JAMA Intern Med. 2014;174(5):817-818. doi:10.1001/jamainternmed.2014.190

Depression and Clinical Inertia in Patients With Uncontrolled Hypertension

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JAMA Intern Med. 2014;174(5):818-819. doi:10.1001/jamainternmed.2014.115

Health Care Reform

Headaches and Neuroimaging: High Utilization and Costs Despite Guidelines

Abstract Full Text
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JAMA Intern Med. 2014;174(5):819-821. doi:10.1001/jamainternmed.2014.173
Comment & Response

Gender Income Disparities Can Be Explained by Alternative Factors—Reply

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JAMA Intern Med. 2014;174(5):822-823. doi:10.1001/jamainternmed.2014.35

Gender Income Disparities Can Be Explained by Alternative Factors

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JAMA Intern Med. 2014;174(5):822-823. doi:10.1001/jamainternmed.2014.48

Will a Policy of Refusing Reimbursement for Health Care–Associated Infections Be a Sufficient Incentive to Drive Improvements?—Reply

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JAMA Intern Med. 2014;174(5):823-824. doi:10.1001/jamainternmed.2014.36

Will a Policy of Refusing Reimbursement for Health Care–Associated Infections Be a Sufficient Incentive to Drive Improvements?

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JAMA Intern Med. 2014;174(5):823. doi:10.1001/jamainternmed.2014.39

Conflict of Interest Disclosures

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JAMA Intern Med. 2014;174(5):823. doi:10.1001/jamainternmed.2014.758

Identifying Livestock-Associated Methicillin-Resistant Staphylococcus aureus in the United States

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JAMA Intern Med. 2014;174(5):824-825. doi:10.1001/jamainternmed.2014.45

Identifying Livestock-Associated Methicillin-Resistant Staphylococus Aureus in the United States—Reply

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JAMA Intern Med. 2014;174(5):825. doi:10.1001/jamainternmed.2014.37

Intensive Glucose Control for Acute Myocardial Infarction: An Unresolved Clinical Conundrum

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JAMA Intern Med. 2014;174(5):825-826. doi:10.1001/jamainternmed.2014.374

Intensive Glucose Control for Acute Myocardial Infarction—Reply

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JAMA Intern Med. 2014;174(5):826-827. doi:10.1001/jamainternmed.2014.343

AACE Response to Viewpoint of December 9, 2013—Reply

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JAMA Intern Med. 2014;174(5):827-828. doi:10.1001/jamainternmed.2014.166

AACE Response to Viewpoint of December 9, 2013

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JAMA Intern Med. 2014;174(5):827. doi:10.1001/jamainternmed.2014.193
Correction

Missing Conflict of Interest Disclosures

Abstract Full Text
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JAMA Intern Med. 2014;174(5):828. doi:10.1001/jamainternmed.2014.1137
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
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JAMA Intern Med. 2014;174(5):660. doi:10.1001/jamainternmed.2013.10651
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