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November 2015, Vol 175, No. 11, Pages 1739-1876

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1739-1741. doi:10.1001/jamainternmed.2014.5094
Viewpoint

Mass Diseases, Mass Exposures, and Mass Media

Abstract Full Text
JAMA Intern Med. 2015;175(11):1743-1744. doi:10.1001/jamainternmed.2015.5079

This Viewpoint details how mass media, often overlooked as a medical tool, can be used to help prevent disease and save lives by communicating simple messages that nearly every patient needs to hear.

Original Investigation

Mediterranean Diet and Invasive Breast Cancer Risk Among Women at High Cardiovascular Risk in the PREDIMED Trial: A Randomized Clinical Trial

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1752-1760. doi:10.1001/jamainternmed.2015.4838

Results of this secondary analysis of the PREDIMED trial suggest a beneficial effect of a Mediterranean diet supplemented with extra-virgin olive oil in the primary prevention of breast cancer.

Shared Decision Making for Antidepressants in Primary Care: A Cluster Randomized Trial

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1761-1770. doi:10.1001/jamainternmed.2015.5214

This cluster randomized trial studied the effectiveness of the Depression Medication Choice decision aid to help patients with moderate to severe depression and clinicians choose antidepressants together and found it improved the decision-making process and quality of care.

Cognitive Behavior Therapy for Depression and Self-Care in Heart Failure Patients: A Randomized Clinical Trial

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1773-1782. doi:10.1001/jamainternmed.2015.5220

This randomized clinical trial aimed to determine if cognitive behavior therapy for depression and self-care in heart failure patients was effective and found that, relative to usual care, the intervention improved depression but not heart failure self-care.

Less Is More

Association of Reference Payment for Colonoscopy With Consumer Choices, Insurer Spending, and Procedural Complications

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1783-1789. doi:10.1001/jamainternmed.2015.4588

This study investigated changes in colonoscopy-related spending and complications before and after institution of an insurer policy that forced cost sharing for use of higher-priced services.

Overdiagnosis of Clostridium difficile Infection in the Molecular Test Era

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1792-1801. doi:10.1001/jamainternmed.2015.4114

This cohort study of hospitalized adults with suspected Clostridium difficile infection compared complications and deaths among those with positive vs negative polymerase chain reaction and toxin immunoassay test results.

Health Care Reform

Patient Characteristics and Differences in Hospital Readmission Rates

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1803-1812. doi:10.1001/jamainternmed.2015.4660

This survey data–based study from the Health and Retirement Study and linked Medicare claims for participants who were hospitalized from 2009 to 2012 assessed the extent to which a comprehensive set of patient characteristics accounts for differences in hospital readmission rates.

Changes in Low-Value Services in Year 1 of the Medicare Pioneer Accountable Care Organization Program

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1815-1825. doi:10.1001/jamainternmed.2015.4525

This population-based study evaluates the effect of the Medicare Pioneer accountable care organization program on the use of what are considered to be low-value services.

Less Is More

Diagnostic Accuracy of Digital Screening Mammography With and Without Computer-Aided Detection

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1828-1837. doi:10.1001/jamainternmed.2015.5231

This study of data pooled from 5 mammography registries found that computer-aided detection (CAD) does not improve diagnostic accuracy of mammography, and these results suggest that insurers pay more for CAD with no established benefit to women.

Risk of Aortic Dissection and Aortic Aneurysm in Patients Taking Oral Fluoroquinolone

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1839-1847. doi:10.1001/jamainternmed.2015.5389

This nested case-control analysis of database records found that use of fluoroquinolones was associated with an increased risk of aortic aneurysm and dissection.

Invited Commentary

The Role of Decision Aids in Depression Care

Abstract Full Text
JAMA Intern Med. 2015;175(11):1770-1772. doi:10.1001/jamainternmed.2015.5243

New Approaches to Controlling Health Care Costs: Bending the Cost Curve for Colonoscopy

Abstract Full Text
JAMA Intern Med. 2015;175(11):1789-1791. doi:10.1001/jamainternmed.2015.4594

Diagnosis of Clostridium difficile Infection: Treat the Patient, Not the Test

Abstract Full Text
JAMA Intern Med. 2015;175(11):1801-1802. doi:10.1001/jamainternmed.2015.4607

The Utility of Unplanned Early Hospital Readmissions as a Health Care Quality Indicator

Abstract Full Text
JAMA Intern Med. 2015;175(11):1812-1814. doi:10.1001/jamainternmed.2015.4727

Precision Health Care Efficiency via Accountable Care Organizations

Abstract Full Text
JAMA Intern Med. 2015;175(11):1825-1827. doi:10.1001/jamainternmed.2015.5322

Is It Time to Stop Paying for Computer-Aided Mammography?

Abstract Full Text
JAMA Intern Med. 2015;175(11):1837-1838. doi:10.1001/jamainternmed.2015.5319

Maintaining Access to Medications When Plans Implement Tiered Pharmacy Networks

Abstract Full Text
JAMA Intern Med. 2015;175(11):1853-1854. doi:10.1001/jamainternmed.2015.4994
Editor's Note

Mass Media Campaigns to Prevent Chronic Disease—A Powerful but Underused Tool

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1745. doi:10.1001/jamainternmed.2015.5546

Can Diet Prevent Breast Cancer?

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1760. doi:10.1001/jamainternmed.2015.5053

Reframing Depression Treatment in Heart Failure

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1782. doi:10.1001/jamainternmed.2015.5240

Global Drug Safety Insights From Taiwan

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1847. doi:10.1001/jamainternmed.2015.5402

Appropriate Use Criteria Require Data

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1855-1856. doi:10.1001/jamainternmed.2015.5050

Would a Breakthrough Therapy by Any Other Name Be as Promising?

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1858-1859. doi:10.1001/jamainternmed.2015.5311
Teachable Moment

Less Is More

Diarrhea With Clostridium difficile–Positive Stool—Trick or Treat: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2015;175(11):1746-1747. doi:10.1001/jamainternmed.2015.4792

This case study serves as a reminder that the routine diagnostic tests for C difficile do not distinguish between active disease and colonization and that clinicians must consider, when appropriate, other potential causes of diarrhea, both infectious and noninfectious.

Less Is More

Inappropriate Antibiotic Therapy in a Patient With Heart Failure and Prolonged QT Interval: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2015;175(11):1748-1749. doi:10.1001/jamainternmed.2015.5047

This case illustrates how unnecessary antibiotic use might cause life-threatening adverse events in the context of certain types of heart disease.

Less Is More

Hospice Diagnosis: Polypharmacy: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2015;175(11):1750-1751. doi:10.1001/jamainternmed.2015.5253

This Teachable Moment highlights the risk of polypharmacy in the treatment of neuropsychiatric symptoms, the complexity of prognostication in dementia, and the importance of a multifaceted approach to neuropsychiatric symptoms.

Research Letter

Medicare Coverage of Anesthesia Services During Screening Colonoscopies for Patients at Low Risk of Sedation-Related Complications

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1848-1850. doi:10.1001/jamainternmed.2015.4585

This Research Letter examines the costs and potential benefits of Medicare coverage of anesthesia services during screening colonoscopies for patients at low risk of sedation-related complications.

Association Between Narrow Pharmacy Networks and Medication Adherence

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1850-1853. doi:10.1001/jamainternmed.2015.4582

This pharmacoepidemiology study assessed medication adherence before and after implementation of narrow insurance networks within commercial drug plans.

Less Is More

Low Yield of Myocardial Perfusion Imaging in Asymptomatic Patients With Atrial Fibrillation

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1854-1855. doi:10.1001/jamainternmed.2015.4802

In this single-center study of asymptomatic patients with atrial fibrillation, the yield for detecting ischemia with myocardial perfusion imaging was low and did not significantly increase with increasing clinical risk.

A Randomized Trial Testing US Food and Drug Administration “Breakthrough” Language

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1856-1858. doi:10.1001/jamainternmed.2015.5355

This randomized trial explores why press releases with neutral terms—and that routinely explain the limited evidence supporting accelerating approval—might help consumers make more accurate judgments about drugs with “breakthrough” designation.

Comment & Response

Measurement Methodology: What Does Blood Pressure Mean in the PARTAGE Study?

Abstract Full Text
JAMA Intern Med. 2015;175(11):1859-1860. doi:10.1001/jamainternmed.2015.4627

Measurement Methodology: What Does Blood Pressure Mean in the PARTAGE Study?—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(11):1860. doi:10.1001/jamainternmed.2015.4630

Careful Considerations Concerning Psychogenic Itch

Abstract Full Text
JAMA Intern Med. 2015;175(11):1861. doi:10.1001/jamainternmed.2015.4677

Careful Considerations Concerning Psychogenic Itch—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(11):1861-1862. doi:10.1001/jamainternmed.2015.4680

Shared Decision-Making for Cancer Screening: Visual Tools and a 4-Step Method

Abstract Full Text
JAMA Intern Med. 2015;175(11):1862. doi:10.1001/jamainternmed.2015.4721

Physical Activity and Successful Aging: Even a Little Is Good

Abstract Full Text
JAMA Intern Med. 2015;175(11):1862-1863. doi:10.1001/jamainternmed.2015.4744

Physical Activity and Successful Aging—Reply: Even a Little Is Good

Abstract Full Text
JAMA Intern Med. 2015;175(11):1863-1864. doi:10.1001/jamainternmed.2015.4747

Physical Activity Is Key for Successful Aging—Reply: Even a Little Is Good

Abstract Full Text
JAMA Intern Med. 2015;175(11):1863. doi:10.1001/jamainternmed.2015.4750

Dosing Strategies of Bone-Targeting Agents

Abstract Full Text
JAMA Intern Med. 2015;175(11):1864-1865. doi:10.1001/jamainternmed.2015.4789

Dosing Strategies of Bone-Targeting Agents

Abstract Full Text
JAMA Intern Med. 2015;175(11):1865. doi:10.1001/jamainternmed.2015.4796

Dosing Strategies of Bone-Targeting Agents—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(11):1865-1866. doi:10.1001/jamainternmed.2015.4799

Appropriate Care of a Swollen Joint

Abstract Full Text
JAMA Intern Med. 2015;175(11):1866. doi:10.1001/jamainternmed.2015.5068

Appropriate Care of a Swollen Joint—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(11):1866-1867. doi:10.1001/jamainternmed.2015.5071

The True Environmental Cost of Chlorofluorocarbon-Based Inhalers

Abstract Full Text
JAMA Intern Med. 2015;175(11):1867. doi:10.1001/jamainternmed.2015.5237

Less Is More

The Lariat for Left Atrial Appendage Closure: Rehash of Known Literature or a True Analysis?

Abstract Full Text
JAMA Intern Med. 2015;175(11):1867-1868. doi:10.1001/jamainternmed.2015.5386

The Lariat for Left Atrial Appendage Closure: Rehash of Known Literature or a True Analysis?

Abstract Full Text
JAMA Intern Med. 2015;175(11):1868-1869. doi:10.1001/jamainternmed.2015.5399

Less Is More

The Lariat for Left Atrial Appendage Closure: Rehash of Known Literature or a True Analysis?—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(11):1869-1870. doi:10.1001/jamainternmed.2015.5405

US Department of Veterans Affairs Primary Care Provider Turnover and Patient Satisfaction

Abstract Full Text
JAMA Intern Med. 2015;175(11):1870. doi:10.1001/jamainternmed.2015.5408

US Department of Veterans Affairs Primary Care Provider Turnover and Patient Satisfaction—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(11):1870-1871. doi:10.1001/jamainternmed.2015.5411

Whole-Arm Ultrasound for Suspected Upper-Extremity Deep Venous Thrombosis in Outpatients

Abstract Full Text
JAMA Intern Med. 2015;175(11):1871. doi:10.1001/jamainternmed.2015.5450

Whole-Arm Ultrasound for Suspected Upper-Extremity Deep Venous Thrombosis in Outpatients—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(11):1871-1872. doi:10.1001/jamainternmed.2015.5460

Subclinical Hypothyroidism Overdiagnosis in Pregnant Women

Abstract Full Text
JAMA Intern Med. 2015;175(11):1872-1873. doi:10.1001/jamainternmed.2015.5550

Subclinical Hypothyroidism Overdiagnosis in Pregnant Women—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(11):1873. doi:10.1001/jamainternmed.2015.5553

Imaging Tests for Suspected Deep Vein Thrombosis

Abstract Full Text
JAMA Intern Med. 2015;175(11):1873-1874. doi:10.1001/jamainternmed.2015.5586

Imaging Tests for Suspected Deep Vein Thrombosis—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(11):1874. doi:10.1001/jamainternmed.2015.5589

Misinterpretation of the Comparative Safety of Testosterone Dosage Forms

Abstract Full Text
JAMA Intern Med. 2015;175(11):1874-1875. doi:10.1001/jamainternmed.2015.5804

Misinterpretation of the Comparative Safety of Testosterone Dosage Forms—Reply

Abstract Full Text
JAMA Intern Med. 2015;175(11):1875-1876. doi:10.1001/jamainternmed.2015.5807
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
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JAMA Intern Med. 2015;175(11):1742. doi:10.1001/jamainternmed.2014.5095
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