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August 2019 - January 1908

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Issue

January 2016, Vol 176, No. 1, Pages 3-143

In This Issue of JAMA Internal Medicine

Highlights

Abstract Full Text
free access
JAMA Intern Med. 2016;176(1):3-5. doi:10.1001/jamainternmed.2015.4852
Viewpoint

Less Is More

Strategies for Flipping the Script on Opioid Overprescribing

Abstract Full Text
JAMA Intern Med. 2016;176(1):7-8. doi:10.1001/jamainternmed.2015.5946

This Viewpoint discusses strategies for prevent overprescribing of opioids while still effectively treating patients in chronic pain.

Health Care Reform

The Role of Government in Health Care Reform in the United States and England

Abstract Full Text
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JAMA Intern Med. 2016;176(1):9-10. doi:10.1001/jamainternmed.2015.6054

This Viewpoint addresses common challenges in the United States and England of increasing health care value by improving quality and discusses how governments have a central role in determining the public-private balance of their health systems.

The Untapped Potential of Pharmacy Leaflets for Informing Patients About Drug Benefits and Risks

Abstract Full Text
JAMA Intern Med. 2016;176(1):11-12. doi:10.1001/jamainternmed.2015.6656

This Viewpoint details how standardized and clearly worded pharmacy leaflets provided with prescription medications could communicate succinct information about the benefits and risks of medications and improve patient expectations, knowledge, and safety.

Corporate Funding of Food and Nutrition Research: Science or Marketing?

Abstract Full Text
JAMA Intern Med. 2016;176(1):13-14. doi:10.1001/jamainternmed.2015.6667

This Viewpoint emphasizes that nutrition researchers and professional societies need to recognize the influence of food-industry sponsorship, take steps to control its effects, and ensure that sponsored studies promote public health.

Perspective

Less Is More

A Proximal Hamstring Injury—Getting Off a Slippery Slope

Abstract Full Text
JAMA Intern Med. 2016;176(1):15-16. doi:10.1001/jamainternmed.2015.6795
Original Investigation

Prescription Strategies in Acute Uncomplicated Respiratory Infections: A Randomized Clinical Trial

Abstract Full Text
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JAMA Intern Med. 2016;176(1):21-29. doi:10.1001/jamainternmed.2015.7088

This trial of patients with uncomplicated respiratory infections randomizes participants to 1 of 4 antibiotic prescription strategies to determine whether delayed antibiotic strategies are associated with greater symptom burden and duration, as well as reduced antibiotic use.

Less Is More

A Comparative Effectiveness Trial of Alternate Formats for Presenting Benefits and Harms Information for Low-Value Screening Services: A Randomized Clinical Trial

Abstract Full Text
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JAMA Intern Med. 2016;176(1):31-41. doi:10.1001/jamainternmed.2015.7339

This clinical trial examines the effect of 3 different presentations of benefits and harms on patients’ intentions to accept low-value or potentially low-value screening services.

Nutritional Support and Outcomes in Malnourished Medical Inpatients: A Systematic Review and Meta-analysis

Abstract Full Text
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JAMA Intern Med. 2016;176(1):43-53. doi:10.1001/jamainternmed.2015.6587

This systematic review and meta-analysis of randomized clinical trials assesses the effects of nutritional support on outcomes of medical inpatients with malnutrition or at risk for malnutrition.

Health Care Reform

Association of Off-label Drug Use and Adverse Drug Events in an Adult Population

Abstract Full Text
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JAMA Intern Med. 2016;176(1):55-63. doi:10.1001/jamainternmed.2015.6058

This cohort study of off-label use of prescription drugs assesses the risks for and prevalence of adverse drug events documented in the electronic health records of adults seeking medical treatment under a national health insurance system.

Cost-effectiveness of Early Treatment of Hepatitis C Virus Genotype 1 by Stage of Liver Fibrosis in a US Treatment-Naive Population

Abstract Full Text
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JAMA Intern Med. 2016;176(1):65-73. doi:10.1001/jamainternmed.2015.6011

This decision-analytic model of treatment for hepatitis C virus genotype 1 assesses the cost-effectiveness of treating all patients with hepatitis C virus infection at all stages of fibrosis vs those with advanced fibrosis only in a US treatment-naive population sample.

Preexposure Prophylaxis for HIV Infection Integrated With Municipal- and Community-Based Sexual Health Services

Abstract Full Text
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JAMA Intern Med. 2016;176(1):75-84. doi:10.1001/jamainternmed.2015.4683

This study tested the efficacy of preexposure prophylaxis for HIV and other sexually transmitted infections in a population of men who have sex with men and transgender women.

Association of Fitness in Young Adulthood With Survival and Cardiovascular Risk: The Coronary Artery Risk Development in Young Adults (CARDIA) Study

Abstract Full Text
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JAMA Intern Med. 2016;176(1):87-95. doi:10.1001/jamainternmed.2015.6309

This review examines whether cardiorespiratory fitness in US young adults is associated with clinical outcomes and subclinical cardiovascular disease at a 25-year follow-up reassessment.

Association of Do-Not-Resuscitate Orders and Hospital Mortality Rate Among Patients With Pneumonia

Abstract Full Text
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JAMA Intern Med. 2016;176(1):97-104. doi:10.1001/jamainternmed.2015.6324

This cohort study evaluates the results of a lack of data on patients’ do-not-resuscitate status as part of mortality outcomes in assessment of a hospital’s quality.

Invited Commentary

Delayed Antibiotic Prescribing Strategies—Time to Implement?

Abstract Full Text
JAMA Intern Med. 2016;176(1):29-30. doi:10.1001/jamainternmed.2015.7095

Patient Decision Aids for Discouraging Low-Value Health Care Procedures: Null Findings and Lessons Learned

Abstract Full Text
JAMA Intern Med. 2016;176(1):41-42. doi:10.1001/jamainternmed.2015.7347

Nutritional Support on the Medical Wards—Thought for Food

Abstract Full Text
JAMA Intern Med. 2016;176(1):53-54. doi:10.1001/jamainternmed.2015.7062

Off-label Drug Use and Adverse Drug Events: Turning up the Heat on Off-label Prescribing

Abstract Full Text
JAMA Intern Med. 2016;176(1):63-64. doi:10.1001/jamainternmed.2015.6068

Treatment of Hepatitis C Virus Infection in Real Life

Abstract Full Text
JAMA Intern Med. 2016;176(1):73-74. doi:10.1001/jamainternmed.2015.6659

Optimizing Delivery of Preexposure Prophylaxis—The Next Frontier

Abstract Full Text
JAMA Intern Med. 2016;176(1):85-86. doi:10.1001/jamainternmed.2015.6530

Fitness in Young Adults as an Independent Predictor of Risk for Cardiovascular Disease

Abstract Full Text
JAMA Intern Med. 2016;176(1):95-96. doi:10.1001/jamainternmed.2015.6819

Implications of Including Do-Not-Resuscitate Status in Hospital Mortality Measures

Abstract Full Text
JAMA Intern Med. 2016;176(1):105-106. doi:10.1001/jamainternmed.2015.6845

Accountability of Hospitals for Medicare Beneficiaries’ Postacute Care Discharge Disposition

Abstract Full Text
JAMA Intern Med. 2016;176(1):119-121. doi:10.1001/jamainternmed.2015.6508

Exclusion of Patients With Kidney Disease From Cardiovascular Trials

Abstract Full Text
JAMA Intern Med. 2016;176(1):124-125. doi:10.1001/jamainternmed.2015.6403

Computers in the Examination Room

Abstract Full Text
JAMA Intern Med. 2016;176(1):128-129. doi:10.1001/jamainternmed.2015.6559

Ongoing Use of Pulmonary Artery Catheters Despite Negative Trial Findings

Abstract Full Text
JAMA Intern Med. 2016;176(1):133-134. doi:10.1001/jamainternmed.2015.6547
Editor's Note

Overpowering Images

Abstract Full Text
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JAMA Intern Med. 2016;176(1):17. doi:10.1001/jamainternmed.2015.6933

Finding the Right Price for Improving Care

Abstract Full Text
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JAMA Intern Med. 2016;176(1):109. doi:10.1001/jamainternmed.2015.7230

Risks Associated With Catheters

Abstract Full Text
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JAMA Intern Med. 2016;176(1):115. doi:10.1001/jamainternmed.2015.6443
Evidence to Practice

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors for Treatment of High Cholesterol Levels: Effectiveness and Value

Abstract Full Text
JAMA Intern Med. 2016;176(1):107-108. doi:10.1001/jamainternmed.2015.7248

This evidence summary reviews the comparative clinical effectiveness of proprotein convertase subtilisin/kexin type 9 inhibitor for the treatment of adults with familial hypercholesterolemia or cardiovascular disease and who require additional lowering of low-density lipoprotein cholesterol levels.

Teachable Moment

Less Is More

Surgical Intervention in Terminal Illness—Doing Everything: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2016;176(1):18-19. doi:10.1001/jamainternmed.2015.6335

This Teachable Moment describes the case of a man with metastatic masses in his brain who underwent surgery and died shortly thereafter and calls for more careful consideration of treatment options.

Less Is More

Antibiotic Overuse and Paronychia: A Teachable Moment

Abstract Full Text
JAMA Intern Med. 2016;176(1):19-20. doi:10.1001/jamainternmed.2015.6527

This case report uses the example of an older woman with paronychia to discuss judicious use of antibiotics for skin conditions in the outpatient setting.

Challenges in Clinical Electrocardiography

New-Onset Heart Failure in a Patient With a Pacemaker: An Unusual Cause

Abstract Full Text
JAMA Intern Med. 2016;176(1):110-111. doi:10.1001/jamainternmed.2015.6543
Research Letter

Less Is More

Medical Directive for Urinary Catheter Removal by Nurses on General Medical Wards

Abstract Full Text
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JAMA Intern Med. 2016;176(1):113-115. doi:10.1001/jamainternmed.2015.6319

Impacts of a Medical Directive for Urinary Catheter Removal by Nurses

Health Care Reform

Changes in Discharge Location and Readmission Rates Under Medicare Bundled Payment

Abstract Full Text
free access
JAMA Intern Med. 2016;176(1):115-117. doi:10.1001/jamainternmed.2015.6265

This review of Medicare claims data assesses the effect of the Bundled Payment for Care Improvement model on rates of patient discharge to postacute care facilities.

Association of Postdischarge Spending and Performance on New Episode-Based Spending Measure

Abstract Full Text
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JAMA Intern Med. 2016;176(1):117-119. doi:10.1001/jamainternmed.2015.6261

This CMS database study suggests that hospitals that can reduce postdischarge spending may perform better on CMS’ new spending measure.

Representation of Patients With Kidney Disease in Trials of Cardiovascular Interventions: An Updated Systematic Review

Abstract Full Text
free access
JAMA Intern Med. 2016;176(1):121-124. doi:10.1001/jamainternmed.2015.6102

This systematic review of the literature describes patients with kidney disease who are underrepresented in trials of cardiovascular interventions.

Association Between Clinician Computer Use and Communication With Patients in Safety-Net Clinics

Abstract Full Text
free access
JAMA Intern Med. 2016;176(1):125-128. doi:10.1001/jamainternmed.2015.6186

This study reports that high computer use by clinicians in safety-net clinics was associated with lower patient satisfaction and observable communication differences.

Use of Pulmonary Artery Catheterization in US Patients With Heart Failure, 2001-2012

Abstract Full Text
free access
JAMA Intern Med. 2016;176(1):129-132. doi:10.1001/jamainternmed.2015.6190

This survey analysis using data from the National Inpatient Sample evaluates the use of pulmonary artery catheters in patients hospitalized for heart failure in the United States.

Recurrence and Mortality in Young Women With Myocardial Infarction or Ischemic Stroke: Long-term Follow-up of the Risk of Arterial Thrombosis in Relation to Oral Contraceptives (RATIO) Study

Abstract Full Text
free access
JAMA Intern Med. 2016;176(1):134-136. doi:10.1001/jamainternmed.2015.6523

This Research Letter reports the long-term mortality and subtype-specific morbidity in young women surviving myocardial infarction or ischemic stroke.

Preexposure Prophylaxis Awareness and Use in a Population-Based Sample of Young Black Men Who Have Sex With Men

Abstract Full Text
free access
JAMA Intern Med. 2016;176(1):136-138. doi:10.1001/jamainternmed.2015.6536

This cohort study of the uConnect population-based sample of black men who have sex with men discusses the HIV prevention potential of a preexposure prophylaxis approved by the US Food and Drug Administration in 2012.

Comment & Response

Korean National Health Insurance Database

Abstract Full Text
JAMA Intern Med. 2016;176(1):138. doi:10.1001/jamainternmed.2015.7110

Korean National Health Insurance Database—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(1):138-139. doi:10.1001/jamainternmed.2015.7116

Supplementing the Role of Primary Care Physicians

Abstract Full Text
JAMA Intern Med. 2016;176(1):139-140. doi:10.1001/jamainternmed.2015.7163

The Safe Use of Propofol

Abstract Full Text
JAMA Intern Med. 2016;176(1):140. doi:10.1001/jamainternmed.2015.7198

The Safe Use of Propofol—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(1):140. doi:10.1001/jamainternmed.2015.7201

Unreliable Conclusions of Breast Cancer Screening, Incidence, and Mortality

Abstract Full Text
JAMA Intern Med. 2016;176(1):140-141. doi:10.1001/jamainternmed.2015.7204

Unreliable Conclusions of Breast Cancer Screening, Incidence, and Mortality—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(1):141-142. doi:10.1001/jamainternmed.2015.7207

Cardiopulmonary Resuscitation and Benefit to Patients With Metastatic Cancer

Abstract Full Text
JAMA Intern Med. 2016;176(1):142. doi:10.1001/jamainternmed.2015.7415

Cardiopulmonary Resuscitation and Benefit to Patients With Metastatic Cancer—Reply

Abstract Full Text
JAMA Intern Med. 2016;176(1):142-143. doi:10.1001/jamainternmed.2015.7418
Correction

Error in Table

Abstract Full Text
free access
JAMA Intern Med. 2016;176(1):143. doi:10.1001/jamainternmed.2015.7309
JAMA Internal Medicine Masthead

JAMA Internal Medicine

Abstract Full Text
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JAMA Intern Med. 2016;176(1):6. doi:10.1001/jamainternmed.2015.4853
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