July 2016, Vol 176, No. 7, Pages 877-1037

This systematic review and meta-analysis examines the efficacy, tolerability, and dose-dependent effects of opioid analgesics for low back pain.

This randomized clinical trial investigates participation rate, adenoma yield, performance, and adverse events of population-based colonoscopy screening in several European countries.

This randomized clinical trial compares the effects of graphic pictorial vs usual text-based cigarette package health warnings on smoking cessation attempts of smokers.

This randomized clinical trial evaluates the efficacy of telephone-based cognitive behavioral therapy for insomnia vs menopause education control.

This randomized clinical trial examines the effect of an in-hospital mobility program on posthospitalization function and community mobility in hospitalized patients 65 years and older.

This randomised clinical trial examines the effect of patient navigation on breast, cervical, and colorectal cancer screening levels in low-income and racial/ethnic minority populations.

This randomized clinical trial compares the effects on HbA1c levels of adding liraglutide vs placebo to high-dose insulin treatment among patients with type 2 diabetes.

This randomized clinical trial compares centrally assisted collaborative telecare with usual integrated care for military-related posttraumatic stress disorder and depression.

This pharmacoepidemiology study uses claims data to investigate the association between intensive glucose-lowering treatment and severe hypoglycemia among adults with type 2 diabetes between 2001 and 2013.

This cohort study investigates whether referral to the hospital is associated with better outcomes in a population of patients presenting with hypertensive urgency in the office setting.

This random sample analysis estimates the frequency and characteristics of opioid prescribing at hospital discharge among Medicare beneficiaries who had no opioid prescription claim 60 days prior to hospitalization.

This cross-sectional study compares low-value care in the Medicaid and commercially insured populations in Oregon, tests whether provision of low-value care is associated with insurance type, and assesses whether local practice patterns are associated with the provision of low-value care.